Protein Alignment Hdc and hdc

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: XP_017947930.2
• Gene: hdc / 100497702
• XenbaseID: XB-GENE-979207
• Length: 672
• Species: Xenopus tropicalis
• Alignment Length: 480
• Identity: 295/480 - (61%)
• Similarity: 372/480 - (77%)
• Gaps: 6/480 - (1%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            |:.:|||:||||:||||..||..:|||||.|||.|||||.|||:|||:|.|.|.:||.|:|.|:|
 Frog    28 MEPEEYRKRGKELVDYICQYLSTVRERRVNPDVQPGYMRALLPDSAPVESESWERIFRDIEDIIM 92

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            ||:.||||||||||||||.|.|||||||||||||||||||||||||||||:.||:||.||:|||.
 Frog    93 PGVVHWQSPHMHAYFPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVMDWLAKMLGLPC 157

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSS 195
            .|||....|:||||||:|.||:||:.|||.|...|.......|...|:::|:||:||.|:|||||
 Frog   158 HFLHHYPSSKGGGVLQSTVSESTLIALLAARKNKILEMKTSEPDSDDSQLNSRLIAYASNQAHSS 222

  Fly   196 VEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGI 260
            ||||.||.||::|::..|::..:||..|:.|:|:|.|.||||.:|||||||||.|:||.|.|:|.
 Frog   223 VEKAGLISLVKVRFLPVDENFCLRGDTLKAAVEEDRKNGLVPVFVCATLGTTGVCAFDYLAELGP 287

  Fly   261 VCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHR 325
            |||...||||:||||||:||:||||||.:.|::.|||..||||||:|||||.||.||:|...:.:
 Frog   288 VCAREKLWLHIDAAYAGTAFLCPEFRTLMNGVDYADSFTFNPSKWMMVHFDCTAFWVKDKYKLQQ 352

  Fly   326 TFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEAL 390
            ||:|.|:||:|.|:|.|.||||||||||||||:||:|||:||:|:|.||.|||.|..||:.||:|
 Frog   353 TFSVNPIYLRHANTGAATDFMHWQIPLSRRFRSLKLWFVIRSFGVKNLQAHIRHGAELAKYFESL 417

  Fly   391 VLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHTT 455
            |.:|..||:||||||||||||::|.|.:||::|..|...|.::.:|:::..:.:||||:||..||
 Frog   418 VTSDQMFEVPAKRHLGLVVFRLKGPNVLTEEVLAELTKSGKMYLVPATINDELIIRFTVTSQFTT 482

  Fly   456 LDDIVKDWMEIRQVASTVLEEMNIT 480
            .|||::||..|||.|      :|||
 Frog   483 RDDILRDWNLIRQSA------INIT 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	245/377 (65%)
hdc	XP_017947930.2	Pyridoxal_deC	62..440	CDD:395219	245/377 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	534	1.000	Domainoid score	I278
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20490
Inparanoid	1	1.050	636	1.000	Inparanoid score	I816
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223497at33208
OrthoFinder	1	1.000	-	-		FOG0000865
OrthoInspector	1	1.000	-	-		otm49058
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9928
SonicParanoid	1	1.000	-	-		X696
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090