Protein Alignment Hdc and sgpl1

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: XP_005156777.1
• Gene: sgpl1 / 100037312
• ZFINID: ZDB-GENE-070410-24
• Length: 574
• Species: Danio rerio
• Alignment Length: 532
• Identity: 105/532 - (19%)
• Similarity: 174/532 - (32%)
• Gaps: 186/532 - (34%)

  Fly    21 LENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPK------IFSDVERIV-----MPGITHWQSP 74
            |:.|||.....:|:                  |.|      ::...|::.     :.|...|.:|
Zfish   124 LDKIREYETLSEVN------------------WAKGKVSGAVYWGDEKLTDLLVKVYGEFAWTNP 170

  Fly    75 HMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQS 139
            .....||.:..|                          |.|::.|. .....|.||:.
Zfish   171 LHPDIFPGVRKM--------------------------EAEVVRMT-CALFNGGPDSC------- 201

  Fly   140 QGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSSVEKAALIGL 204
               |.:.:..:|:.|:...|.|..|    |||  |.:..||.|.:      ..|::.:|||....
Zfish   202 ---GTVTSGGTESILMACKAYRDMA----HER--GIKHPEIIAPI------SVHAAFDKAAHYFG 251

  Fly   205 VRMRYIEADD-DLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCS--------FDNLEEIGI 260
            :::.::..|: .:.:..|.:|.||..:... ||             ||        .|.:||:..
Zfish   252 MKLIHVPLDNKTMKVDVKAMRRAITKNTAM-LV-------------CSAPQFPHGIMDPVEEVAK 302

  Fly   261 VCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHR 325
            :..::::..||||...|...:.         :|:|.        :.:..||.....|...:|...
Zfish   303 LAVKYNIPFHVDACLGGFLIVF---------MEKAG--------FKLAPFDFRVKGVTSISADTH 350

  Fly   326 TFNVEP------LY----LQHENSGVAVDFMHWQ--IPLSRRFRALK-------VWFVLRSYGIK 371
            .:...|      ||    .:|....||.|   ||  |..|......:       .|..:...|.|
Zfish   351 KYGYAPKGSSVVLYSNRKFRHYQYFVAPD---WQGGIYASPSMAGSRPGGIIAACWATMMHMGEK 412

  Fly   372 GLQRHIREGVRLAQKFEALVLADHRFELPAKRHLGLVVFRIRGDNEITE-----------KLLKR 425
            |.....|:.|...:|.:..:          ::..|:.||   ||.|::.           :|...
Zfish   413 GYVEATRKVVETTRKIKTGI----------RKIDGVFVF---GDPEVSVVALGSDDFDIFRLSNA 464

  Fly   426 LNHRG-NLHCI--PSSLKGQYVIRFTITSTHTTLDDIVKDWMEIRQVASTVLEEMNITISNRVYL 487
            |..:| ||:.:  |||      |...:|..||...       ...|..|.|.:|:      .:.:
Zfish   465 LTSKGWNLNTLQFPSS------IHICVTMLHTQSG-------VAEQFISDVKKEV------AIIM 510

  Fly   488 KETKEKNEAFGS 499
            |..|||....|:
Zfish   511 KNPKEKTTGMGA 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	76/416 (18%)
sgpl1	XP_005156777.1	DOPA_deC_like	143..504	CDD:99743	92/469 (20%)