Protein Alignment Hr3 and rorcb

DIOPT Version :10

• Sequence 1: NP_001334718.1
• Gene: Hr3 / 36073
• FlyBaseID: FBgn0000448
• Length: 871
• Species: Drosophila melanogaster
• Sequence 2: NP_001264023.2
• Gene: rorcb / 562258
• ZFINID: ZDB-GENE-040724-215
• Length: 480
• Species: Danio rerio
• Alignment Length: 483
• Identity: 174/483 - (36%)
• Similarity: 258/483 - (53%)
• Gaps: 63/483 - (13%)

  Fly   428 MTAQIEIIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYC 492
            |.||||:||||:|||||||:||||||||||||||||||.:...|.|.|.:.|::||.||||||:|
Zfish     1 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSCSRQRNCLIDRTNRNRCQHC 65

  Fly   493 RLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHH 557
            ||||||.||||||||||||||||||:.:..||:.|:       ..:.|.....|....:.|..|.
Zfish    66 RLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQRHQ-------QLSQDCLAGLTGRDEAEDGAHS 123

  Fly   558 NNYNSGGYSNN----------------------------------EVGYGSPYGYSASVTPQQTM 588
            ..|:|||.|:|                                  ..|.||....|.|.:..|:.
Zfish   124 RPYSSGGSSSNLSDLDDIATLPDGLLFDLPLTPEEAGEYCALEMLSSGTGSGSSGSGSSSSSQSS 188

  Fly   589 QYDISADYVDSTTYEPRSTIIDPEFISHA-------DGDINDV--LIKTLAEAHANT---NTKLE 641
            ....:.|..|:...:....:.|...::|:       :..::|:  :.:.:.::|..|   :|:..
Zfish   189 PEPSAVDLADAVRVKHEYIMPDNSRLTHSLLGSIPDNCSLHDIERITQNVVKSHLETCQYSTEEL 253

  Fly   642 AVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKT 706
            ..|......|:.:|....|:  .|.:|..||.::|..||.::||||.|.|||.|.|:|||:|||.
Zfish   254 KKHTWSLYTPEETRSFQLKS--AEWMWQQCALQITNAIQYVVEFAKRISGFMELCQNDQIILLKA 316

  Fly   707 GSFELAIVRMSRLLDLSQNAVLYGDVMLPQEAFYTSDSEEMRLVSRIFQTAKSIAELKLTETELA 771
            |..|:.::||.|..:.|.|.:.:.......:.|.....::  ||:.:|:.|||::.|:|:|.|:|
Zfish   317 GCLEVLLIRMCRAYNSSNNTMFFDGKFASPQLFKALGCDD--LVNAVFELAKSLSRLQLSEEEMA 379

  Fly   772 LYQSLVLLWPERNGVRGNTEIQRLFNLSMNAIRQELETNHAPLKGDVTVLDTLLNNIPNFRDISI 836
            ||.:.|||.|:|..:..:.::|:|......|::..|..|.|.::    .||.:::.:|..:.|..
Zfish   380 LYSAAVLLAPDRPWLTESQQVQKLQEKVYVALQHSLHMNGATIE----KLDKMVSKLPQMKSICN 440

  Fly   837 LHMESLSKFKLQHPNVV--FPALYKELF 862
            ||::.|..|:|.||...  ||.||:|:|
Zfish   441 LHIDKLEFFRLVHPETAYSFPPLYREVF 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr3	NP_001334718.1	NR_DBD_ROR	430..524	CDD:143526	70/93 (75%)
		NR_LBD	620..862	CDD:472173	79/248 (32%)
rorcb	NP_001264023.2	None