Protein Alignment Hr3 and thrab

DIOPT Version :10

• Sequence 1: NP_001334718.1
• Gene: Hr3 / 36073
• FlyBaseID: FBgn0000448
• Length: 871
• Species: Drosophila melanogaster
• Sequence 2: XP_009304995.1
• Gene: thrab / 558427
• ZFINID: ZDB-GENE-060613-1
• Length: 419
• Species: Danio rerio
• Alignment Length: 503
• Identity: 128/503 - (25%)
• Similarity: 208/503 - (41%)
• Gaps: 154/503 - (30%)

  Fly   411 RENSR---EHSSSSSGSN----GAMTAQIE-IIPCKVCGDKSSGVHYGVITCEGCKGFFRRS-QS 466
            |:||:   :..|.||.||    |.:.:.:| ..||.|||||::|.||..||||||||||||: |.
Zfish    28 RKNSQCSVKSMSVSSTSNPISQGYIPSYLEKDEPCVVCGDKATGYHYRCITCEGCKGFFRRTIQK 92

  Fly   467 SV-VNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRD-------AVKFGRMSKKQREKVEDE 523
            :: .:|.|..:..|::|::.||:||.||.:||:.:||:.|       .|...|:.::.|||.:.|
Zfish    93 NLHPSYSCKYDGCCIIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRRLIEENREKRKKE 157

  Fly   524 VRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSGGYSNNEVGYGSPYGYSASVTPQQTM 588
            ......|.|.:    |.||.::
Zfish   158 EMVKTLQNRPE----PTSSEWE------------------------------------------- 175

  Fly   589 QYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDV 653
                                                ||:.:.|||.:||.  :..|   .||
Zfish   176 ------------------------------------LIRVVTEAHRHTNA--QGSH---WKQ--- 196

  Fly   654 SRILYYKNLGQE-------------ELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLK 705
            .|....:::||.             |.:.:..:.:|..|..:::|||.:|.|..|..:|||:|||
Zfish   197 KRKFLPEDIGQSPVAPTSDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLK 261

  Fly   706 TGSFELAIVRMSRLLD-LSQNAVLYGDVMLPQEAFYTSDSEEMRLVS-RIFQTAKSIAELKLTET 768
            ....|:..:|.:...| .|:...|.|::.:.:|......   :.:|| .||...||:|:..|.:|
Zfish   262 GCCMEIMSLRAAVRYDPESETLTLSGEMAVKREQLKNGG---LGVVSDAIFDLGKSLAQFNLDDT 323

  Fly   769 ELALYQSLVLLWPERNGVRGNTEIQRLFNLSMNAIRQELETNHAPLKGDVTVLDTLLNNIPNF-- 831
            |:||.|:::|:..:|.|:....:|::...:.:.|....:....              :|||:|
Zfish   324 EVALLQAVLLMSSDRTGLTCVEKIEKCQEMYLLAFEHYINYRK--------------HNIPHFWP 374

  Fly   832 ---------RDISILHMESLSKFKLQHPNVVFPALYKELFSIDSQQDL 870
                     |.|...|.......|::.|..:||.|:.|:|   ..||:
Zfish   375 KLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVF---EDQDV 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr3	NP_001334718.1	NR_DBD_ROR	430..524	CDD:143526	44/103 (43%)
		NR_LBD	620..862	CDD:472173	66/267 (25%)
thrab	XP_009304995.1	NR_DBD_TR	61..147	CDD:143519	40/85 (47%)
		NR_LBD_TR	171..413	CDD:132733	67/345 (19%)