Protein Alignment Hr3 and nhr-23

DIOPT Version :9

• Sequence 1: NP_001334718.1
• Gene: Hr3 / 36073
• FlyBaseID: FBgn0000448
• Length: 871
• Species: Drosophila melanogaster
• Sequence 2: NP_001020975.1
• Gene: nhr-23 / 172460
• WormBaseID: WBGene00003622
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 493
• Identity: 184/493 - (37%)
• Similarity: 249/493 - (50%)
• Gaps: 115/493 - (23%)

  Fly   428 MTAQIEIIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYC 492
            ::||||:|||||||||||||||||||||||||||||||||:|||||||.|.||||||||||||||
 Worm   154 VSAQIEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQKNCVVDRVNRNRCQYC 218

  Fly   493 RLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSS----- 552
            ||:||::||||||||||||||||||||||||||.|:   ...::.....::|...:|..|
 Worm   219 RLKKCIELGMSRDAVKFGRMSKKQREKVEDEVRMHK---ELAANGLGYQAIYGDYSPPPSHPSYC 280

  Fly   553 -DQLHHNNYNSGGYSNNEVGYGSPYGYSASV-----TPQQTMQYDISADYVDSTTYEPRSTIIDP 611
             ||..:.:|.||  ::..|.     |||.:|     ||.....|..:....:.|.|
 Worm   281 FDQSMYGHYPSG--TSTPVN-----GYSIAVAATPTTPMPQNMYGATPSSTNGTQY--------- 329

  Fly   612 EFISH-ADG-----------DINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQ 664
              ::| |.|           |:...:|:...:.|::..|:    |.:....||.  |.:....|.
 Worm   330 --VAHQATGGSFPSPQVPEEDVATRVIRAFNQQHSSYTTQ----HGVCNVDPDC--IPHLSRAGG 386

  Fly   665 EELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSRLLDLSQNAVLY 729
            .||:   |.:|..:||.||||||.|.|||.|.|:.||.|||...|||::|..:...::...||..
 Worm   387 WELF---ARELNPLIQAIIEFAKSIDGFMNLPQETQIQLLKGSVFELSLVFAAMYYNVDAQAVCG 448

  Fly   730 GDVMLPQEAFYTSDSEEMRLVSRIFQTAKSIAELKLTETELALYQSLVLLWPERNGVRGNTEIQR 794
            ....:|.......|..||:|:..:..|.:.|..|:..::||||
 Worm   449 ERYSVPFACLIAEDDAEMQLIVEVNNTLQEIVHLQPHQSELAL---------------------- 491

  Fly   795 LFNLSMNAIRQELETNHAPLKGDVTVLDT-----------------------LLNNIPNFRDISI 836
               |:...|.:::.::|.     :.:|||                       :.:.|...:|:..
 Worm   492 ---LAAGLILEQVSSSHG-----IGILDTATIATAETLKNALYQSVMPRIGCMEDTIHRIQDVET 548

  Fly   837 -------LHMESLSKFKLQHP--NVVFPALYKELFSID 865
                   ||.|:|..|::..|  :...||||||||:.|
 Worm   549 RIRQTARLHQEALQNFRMSDPTSSEKLPALYKELFTAD 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr3	NP_001334718.1	None
nhr-23	NP_001020975.1	NR_DBD_ROR	156..250	CDD:143526	86/93 (92%)
		NR_LBD	384..580	CDD:299703	59/228 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	146	1.000	Domainoid score	I2816
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38250
Inparanoid	1	1.050	278	1.000	Inparanoid score	I1769
Isobase	1	0.950	-	0	Normalized mean entropy	S5442
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001077
OrthoInspector	1	1.000	-	-		oto17544
orthoMCL	1	0.900	-	-		OOG6_104672
Panther	1	1.100	-	-	LDO	PTHR45805
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X649
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.910