Protein Alignment Hr3 and Eip78C

DIOPT Version :10

• Sequence 1: NP_001334718.1
• Gene: Hr3 / 36073
• FlyBaseID: FBgn0000448
• Length: 871
• Species: Drosophila melanogaster
• Sequence 2: XP_061499458.1
• Gene: Eip78C / 1277155
• VectorBaseID: AGAMI1_002616
• Length: 595
• Species: Anopheles gambiae
• Alignment Length: 623
• Identity: 174/623 - (27%)
• Similarity: 279/623 - (44%)
• Gaps: 111/623 - (17%)

  Fly   324 DPPALARSSSFSSLSS----------------FSSISNISSVCKNMASNTSQEGSLKRTKERTPP 372
            ||....|..|.:.:..                |......|:.....:.:.|.|.:.:.|     |
Mosquito     7 DPSGTGRCPSLAKIDEDLAEVHFDTGSEFNLHFFDTPEDSNTQSGFSDHESSESAARDT-----P 66

  Fly   373 PMPPLTT----------HKPAATTTATSA--TSAAAATSAATASATATSARENSREHSSS----- 420
            |.|..:|          |..:.::.|...  .||..:.:....|:||.:|.|.::..|||
Mosquito    67 PSPVCSTPTRGGLRQQQHTNSGSSNAGGGGLVSAIGSGNCVMISSTAHTAMERTKVSSSSYDAGG 131

  Fly   421 ------------SSGSNGAMTAQIEIIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQC 473
                        .|.::...||: ..:.|||||||:||.||||.:|||||||||||....:.|:|
Mosquito   132 QRACAGVRADPLCSDASSTTTAK-TFVACKVCGDKASGYHYGVTSCEGCKGFFRRSIQKQIEYRC 195

  Fly   474 PRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAA 538
            .|:.:|:|.|:|||||||||.:|||.:|||||:|::||:.||.||              |.|.:.
Mosquito   196 LRDGKCLVIRLNRNRCQYCRFKKCLSVGMSRDSVRYGRVPKKSRE--------------AGSCSE 246

  Fly   539 PDSSV-YDTQTPSSSDQLHHNNYNSG-GYSNN---------EVGYGSPYGYSASVT--------- 583
            .:.|: .::.||::..|  |.|.:.| |:|.|         .:|.|:..|.:.|.|
Mosquito   247 ENMSICVNSTTPATGPQ--HGNGSLGTGHSANGTMPTTTTSTLGSGNNAGNNTSATIGHSNGPPS 309

  Fly   584 PQQTMQYDISADYVDST-TYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMF 647
            ...:|..:..|:...|| |..|.|....|..:|..|      :|:.:|:||....|   ...:..
Mosquito   310 SNASMAANSCAEISTSTGTILPDSLTFTPPELSVYD------IIQCIAQAHRGHCT---YTSEQV 365

  Fly   648 RKQPDVSRILY------YKNLGQEELWL--DCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLL 704
            ::|..||.:.|      .::|..:.:||  ..|.::|..:|.|:||||.:|||....||||::|:
Mosquito   366 KEQSRVSLLNYSEKHNPLESLEDQRIWLWQQYAMRMTPAVQRIVEFAKRVPGFGEFLQDDQLILI 430

  Fly   705 KTGSFELAIVRMSRLLDLSQNAVLYGDVMLPQEAFYTSDSEEMRLVSRIFQTAKSIAELKLTETE 769
            |.|.||:.:..::|..:.|......|..:..|:.....|.|   ..:.:|.....:....|::||
Mosquito   431 KLGFFEVWLTHVARATNDSTITFDDGVYITRQQLEVIYDPE---YANALFNFTSGLNSCCLSDTE 492

  Fly   770 LALYQSLVLLWPERNGVRGNTEIQRLFNLSMNAIRQELETNHAPL-KGDVTVLDTLLNNIPNFRD 833
            :.||.:|:|| .:|.|:.....|.:.......|:|.::..:.|.. .|.:.::..|...:...|.
Mosquito   493 IGLYSALILL-SDRPGLVETKLILKTRECIAEALRVQITRSRANNGMGALQIMPALEARVHELRM 556

  Fly   834 ISILHMESLSKFKLQHPNVVFPALYKELFSIDS-QQDL 870
            :...|...|..|:.....:..|.|:.|:|.:.. ::||
Mosquito   557 LGEKHSAHLEWFRTNWSTIRLPPLFAEIFDVPKCEEDL 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr3	NP_001334718.1	NR_DBD_ROR	430..524	CDD:143526	55/93 (59%)
		NR_LBD	620..862	CDD:472173	62/250 (25%)
Eip78C	XP_061499458.1	None