Protein Alignment Hr3 and rarb

DIOPT Version :10

• Sequence 1: NP_001334718.1
• Gene: Hr3 / 36073
• FlyBaseID: FBgn0000448
• Length: 871
• Species: Drosophila melanogaster
• Sequence 2: XP_002932450.2
• Gene: rarb / 100488600
• XenbaseID: XB-GENE-481009
• Length: 447
• Species: Xenopus tropicalis
• Alignment Length: 500
• Identity: 121/500 - (24%)
• Similarity: 199/500 - (39%)
• Gaps: 153/500 - (30%)

  Fly   402 TASATATSARENSR------------EHSSSSSGSNGAMTAQIEII--------------PCKVC 440
            |||.::...:|.:.            :|..|:.......|:..:::              ||.||
 Frog    20 TASPSSCMLQEKALKACFNGLAQTDWQHRHSAQSIETQSTSSEDLVPSPPSPPPPPRIYKPCFVC 84

  Fly   441 GDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRD 505
            .|||||.||||..|||||||||||....:.|.|.|.|.||:::|.||||||||||:|.::|||::
 Frog    85 QDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHREKNCVINKVTRNRCQYCRLQRCFEVGMSKE 149

  Fly   506 AVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSGGYSNNEV 570
            :|:..| :||::|                              ||..:.:.:
 Frog   150 SVRNDR-NKKKKE------------------------------PSKIECIEN------------- 170

  Fly   571 GYGSPYGYSASVTPQQTMQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHAN 635
                               |:::|:.                          |.|.:.:.:||..
 Frog   171 -------------------YEMTAEL--------------------------DDLTEKIRKAHQE 190

  Fly   636 TNTKLEAVHDMFRKQPDVSRI-LYYKNLGQEE-------LWLDCAEKLTQMIQNIIEFAKLIPGF 692
            |             .|.:.:: .|..|...|:       ||...:|..|:.|..|:||||.:|||
 Frog   191 T-------------FPSLCQLGKYTTNSSAEQRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGF 242

  Fly   693 MRLSQDDQILLLKTGSFELAIVRMSRLLDLSQNAVLYGDVMLPQEAFYTSDSEEMR------LVS 751
            ..|:..|||.|||....::.|:|:.......|:.:.:.|.:       |.:..:|.      |..
 Frog   243 TSLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGL-------TLNRTQMHNAGFGPLTD 300

  Fly   752 RIFQTAKSIAELKLTETELALYQSLVLLWPERNGVRGNTEIQRLFNLSMNAIRQELETNHAPLKG 816
            .:|..|..:..|::.:||..|..::.|:..:|..:....::.:|....:.|::..:. ...|.|.
 Frog   301 LVFTFANQLLPLEMDDTETGLLSAICLICEDRQDLEEPAKVDKLQEPLLEALKIYIR-KRRPNKP 364

  Fly   817 DVTVLDTLLNNIPNFRDISILHMESLSKFKLQHPNVVFPALYKEL 861
            .  :...:|..|.:.|.||....|.:...||:.|..: |.|.:|:
 Frog   365 H--MFPKILMKITDLRSISAKGAERVITLKLEIPGSM-PPLIQEM 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr3	NP_001334718.1	NR_DBD_ROR	430..524	CDD:143526	50/107 (47%)
		NR_LBD	620..862	CDD:472173	60/255 (24%)
rarb	XP_002932450.2	NR_DBD_RAR	75..159	CDD:143522	48/84 (57%)
		NR_LBD_RAR	179..409	CDD:132735	59/251 (24%)