DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mlt and tbcela

DIOPT Version :9

Sequence 1:	NP_001260853.1	Gene:	mlt / 36072	FlyBaseID:	FBgn0265512	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_957047.1	Gene:	tbcela / 393726	ZFINID:	ZDB-GENE-040426-1719	Length:	155	Species:	Danio rerio

Alignment Length:	114	Identity:	46/114 - (40%)
Similarity:	66/114 - (57%)	Gaps:	4/114 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PRLSPL---TSVPALLVLNDCDIDSAGDFDSIREKCQRVRELDLAQNKLSDWSEVFSILEHMPRI 113
            |:.||:   .::|::||||.|.|..|||...|...|..|.||||:.|||.||.|:..|:.::|.:
Zfish    41 PQGSPMKDRLNLPSVLVLNGCGISHAGDQGEIAAFCAHVVELDLSHNKLQDWHEISKIVSNVPNL 105

  Fly   114 EFLNLSKNQLASPIGTLPTAPTI-NLKSLVLNGTYLDWACVDTLLKNLP 161
            ||||||.|||:..:.....|... :::..|||.|.:.|..|.|..:.:|
Zfish   106 EFLNLSSNQLSDAVLDPDCAKAFSSIRRFVLNNTQVSWDTVHTFTQEMP 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mlt	NP_001260853.1	LRR	<46..>177	CDD:227223	46/114 (40%)
		LRR_RI	57..>276	CDD:238064	43/109 (39%)
		leucine-rich repeat	87..112	CDD:275380	12/24 (50%)
		leucine-rich repeat	113..137	CDD:275380	10/24 (42%)
		leucine-rich repeat	138..162	CDD:275380	8/24 (33%)
		leucine-rich repeat	207..232	CDD:275380
		leucine-rich repeat	233..260	CDD:275380
		leucine-rich repeat	261..285	CDD:275380
		UBQ	379..456	CDD:294102
tbcela	NP_957047.1	leucine-rich repeat	55..78	CDD:275380	11/22 (50%)
		LRR_8	78..141	CDD:290566	27/62 (44%)
		leucine-rich repeat	79..104	CDD:275380	12/24 (50%)
		LRR_4	81..117	CDD:289563	21/35 (60%)
		leucine-rich repeat	105..130	CDD:275380	10/24 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595832
Domainoid	1	1.000	58	1.000	Domainoid score	I10788
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	269	1.000	Inparanoid score	I2993
OMA	1	1.010	-	-		QHG49290
OrthoDB	1	1.010	-	-		D1495296at2759
OrthoFinder	1	1.000	-	-		FOG0006363
OrthoInspector	1	1.000	-	-		otm26242
orthoMCL	1	0.900	-	-		OOG6_107210
Panther	1	1.100	-	-	LDO	PTHR15140
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2217
SonicParanoid	1	1.000	-	-		X4632
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.940