DRSC/TRiP Functional Genomics Resources

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Protein Alignment mlt and tbce-1

DIOPT Version :9

Sequence 1:NP_001260853.1 Gene:mlt / 36072 FlyBaseID:FBgn0265512 Length:459 Species:Drosophila melanogaster
Sequence 2:NP_501395.1 Gene:tbce-1 / 177624 WormBaseID:WBGene00019503 Length:493 Species:Caenorhabditis elegans


Alignment Length:391 Identity:92/391 - (23%)
Similarity:156/391 - (39%) Gaps:92/391 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 RELDLAQNKLSDWSEVFSILEHMPRIEFLNLSKNQLASPIGTLPTAPTIN--------------- 137
            |||:|..|.|..|..|..|||:.|||:.|||.:|::          ...|               
 Worm   145 RELNLYGNLLYKWKTVRQILEYFPRIQELNLRRNRM----------QCFNEEEDDDESEGDDHVY 199

  Fly   138 ---LKSLVLNGTYLDWACVDTLLKNLPVLQELHLSLNNYRQVLIDAEEAEQRLQETETPEETERR 199
               .|.||::...|....:|::|...|...::....|:..:..: :|....||...:..:...: 
 Worm   200 SDSCKKLVISECNLSENSIDSILLRFPSTSDVVAFGNDLTRFSV-SEAVSSRLTSLDLEDNPFK- 262

  Fly   200 ITKAHPALKTLHFTGNPVEHWQEICRLGRLFPNLEALVLADCPIKSLQAEESSETHRYFPSLRLL 264
                  .|.::|.|                ||||..|.:|:|.|.||...:.|..   ||.|..|
 Worm   263 ------TLDSIHGT----------------FPNLTQLSVANCGITSLNGFDGSIK---FPKLEYL 302

  Fly   265 NLSSAQLDSWAAIDELAKFSELRNLRVKHWPLWESLEC----TEH--ERRQLLIARLPNVEMLNG 323
            |:....:..|.:::.:.....|:.|         ..:|    ||.  ...:::||:|..:..|| 
 Worm   303 NIKRNSIVEWKSVNSIRSLKSLKRL---------LFDCKKLSTEKGVHAYEIVIAKLSTLIDLN- 357

  Fly   324 GGKISSDERVDSERAFVRYYMD-KPEEERPARYQELLQIHGKLDPLVNVSLKPDKRVKVLFTYND 387
            ...:|..||..:|..|:..|.. ...|:.....:.|::|||  :|.::.:.|....||:.....:
 Worm   358 RFDVSEVERRSAEIRFLNKYAGLNDNEDHQDDIKRLIEIHG--EPTLDTAKKGLAVVKIRIECGN 420

  Fly   388 VSESRFVDIYLTVNDLKVKLEKLVGLAPN--KMRLYY------------LDQDYKEFG---PEEM 435
            ..|:|.:.:.:::..::..|.:|..: ||  |:|||.            |:...:|||   |.|.
 Worm   421 RVETRRLPLGMSIQKIRDMLARLFKV-PNTSKIRLYLVMSEKAKQHRIELENPLREFGHYSPSED 484

  Fly   436 R 436
            |
 Worm   485 R 485

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mltNP_001260853.1 LRR <46..>177 CDD:227223 27/106 (25%)
LRR_RI 57..>276 CDD:238064 50/205 (24%)
leucine-rich repeat 87..112 CDD:275380 11/23 (48%)
leucine-rich repeat 113..137 CDD:275380 5/23 (22%)
leucine-rich repeat 138..162 CDD:275380 6/23 (26%)
leucine-rich repeat 207..232 CDD:275380 4/24 (17%)
leucine-rich repeat 233..260 CDD:275380 9/26 (35%)
leucine-rich repeat 261..285 CDD:275380 4/23 (17%)
UBQ 379..456 CDD:294102 19/75 (25%)
tbce-1NP_501395.1 CAP_GLY 3..65 CDD:214997
leucine-rich repeat 145..169 CDD:275380 11/23 (48%)
leucine-rich repeat 170..205 CDD:275380 6/44 (14%)
LRR_RI <204..372 CDD:393385 45/204 (22%)
leucine-rich repeat 206..233 CDD:275380 6/26 (23%)
leucine-rich repeat 251..273 CDD:275380 5/44 (11%)
leucine-rich repeat 274..298 CDD:275380 9/26 (35%)
leucine-rich repeat 299..323 CDD:275380 4/23 (17%)
Ubl_TBCE 410..491 CDD:340564 19/77 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2217
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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