| Sequence 1: | NP_788300.3 | Gene: | KCNQ / 36071 | FlyBaseID: | FBgn0033494 | Length: | 993 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004761.2 | Gene: | KCNB2 / 9312 | HGNCID: | 6232 | Length: | 911 | Species: | Homo sapiens |
| Alignment Length: | 703 | Identity: | 156/703 - (22%) |
|---|---|---|---|
| Similarity: | 256/703 - (36%) | Gaps: | 217/703 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 58 QSRLYNFLERPRGLHA--IFYHVMVFLMVFTCLALSVFSTIKEYEEDAVY-------ILFRMEIL 113
Fly 114 VVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSG-------- 170
Fly 171 -----QVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFL 230
Fly 231 VYMWEKDVN-DKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILG 294
Fly 295 SGFALKVQQQQRQKHMIRRRQP-----------AATLIQAVWRCY------------------AA 330
Fly 331 DEHSVSVATWNIHRVALPSPPASRASSSFKHNTSFVARLPTIRRHKSQTIQTPGGGDGGGVSKPP 395
Fly 396 GSSRASTRYTRTIRDINASVENLEVVQN----------------GKSMNPSFSED---------- 434
Fly 435 ----SVAETTCLKNIKNSDASQPATLANCKLS-----------SSAGSL-AQFPDRNRDRDQDRR 483
Fly 484 GHGEGEGDQAEEQAKAGGSRRNLTI---PVVLYGFLHGNFLGSTLSLRNPRVA------------ 533
Fly 534 ---PANDRDLEAGRDEDEVHKDTCQRSNTLPLPV--------------------------KP--- 566
Fly 567 ---DSPSGSPGSGRTGRF-----FAAASH----FLETGFSSPNPIIDVANEED 607 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNQ | NP_788300.3 | Ion_trans | 100..305 | CDD:278921 | 62/225 (28%) |
| Ion_trans_2 | 221..295 | CDD:285168 | 29/74 (39%) | ||
| KCNQ_channel | <619..719 | CDD:281513 | |||
| KCNB2 | NP_004761.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..22 | ||
| BTB | 37..143 | CDD:197585 | |||
| BTB_2 | 37..136 | CDD:280393 | |||
| Ion_trans | 230..428 | CDD:278921 | 61/214 (29%) | ||
| Ion_trans_2 | 341..422 | CDD:285168 | 30/80 (38%) | ||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 381..386 | 4/4 (100%) | |||
| Kv2channel | 471..759 | CDD:281514 | 58/324 (18%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 503..534 | 9/55 (16%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 549..571 | 3/21 (14%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 637..665 | 5/30 (17%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 685..739 | 9/53 (17%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 760..865 | 14/64 (22%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 892..911 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||