Protein Alignment KCNQ and kcna6a

DIOPT Version :10

• Sequence 1: NP_788300.3
• Gene: KCNQ / 36071
• FlyBaseID: FBgn0033494
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: NP_001124098.1
• Gene: kcna6a / 795490
• ZFINID: ZDB-GENE-080722-21
• Length: 475
• Species: Danio rerio
• Alignment Length: 340
• Identity: 87/340 - (25%)
• Similarity: 139/340 - (40%)
• Gaps: 82/340 - (24%)

  Fly    24 RPNSERILQPRMS--LLGKPLN------------YNRGTRRDV-RYRRLQSRLYNFLERP----- 68
            ||:.:.||....|  .|.:|:|            |..|.  || ::.:....|....|||
Zfish    80 RPSFDAILYYYQSGGRLRRPINVPVDMFLDEIKFYEIGD--DVIKHFQEDEGLLKEDERPLPSNE 142

  Fly    69 --RGLHAIFYH--------------VMVFL--MVFTCLALSVFSTIKEYEED------------- 102
              |.:..:|.|              |||.|  ::..|:     .|:.|:.||
Zfish   143 FKRQIWLLFEHPDSSGAARIIAIVSVMVILISIIIFCI-----ETLPEFREDDRVFDNHLPANST 202

  Fly   103 ------AVYI--LFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILA 159
                  :.|.  .|.:|.:.::||..|...         |:..|..:..|.|.....||||.|:.
Zfish   203 TSVQRLSAYTDPFFLLETICIVWFCFELFI---------RFLACPSKPTFFKDIMNTIDIVAIMP 258

  Fly   160 SIVVLGM------GTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMY 218
            ..:.|.:      ....|..:.:.||.:|..::.|:.::.|.....::||..:.|..:||...::
Zfish   259 YFITLSLELGEVQSNQQQTTSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIF 323

  Fly   219 IGFLGLIFASFLVYMWE-KDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLG 282
            ...:|:|..|..||..| .|....|::...|.||.|:::.|||||||.|:|..||::.|.||:.|
Zfish   324 FLIIGIILFSSAVYFAEADDPETSFTSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSMCAIAG 388

  Fly   283 ISFFALPAGILGSGF 297
            :...|||..::.|.|
Zfish   389 VLTIALPVPVIVSNF 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNQ	NP_788300.3	Ion_trans	72..305	CDD:459842	70/270 (26%)
		KCNQ_channel	<619..719	CDD:460954
kcna6a	NP_001124098.1	BTB_POZ	31..157	CDD:453885	19/78 (24%)
		Ion_trans	203..411	CDD:459842	59/210 (28%)