Protein Alignment KCNQ and Shal

DIOPT Version :9

• Sequence 1: NP_788300.3
• Gene: KCNQ / 36071
• FlyBaseID: FBgn0033494
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Alignment Length: 441
• Identity: 107/441 - (24%)
• Similarity: 179/441 - (40%)
• Gaps: 129/441 - (29%)

  Fly    10 FYDIRGYKGKCRPGRPNSERILQPRMSLLGKPLNYNRGTRRDVRYRRLQSRLYNFLERPRGLHA- 73
            :.|.|..|      |.|:||::..::|        ..|.:...:...::.:::...|.|   |.
  Fly   134 YEDYRDRK------RENAERLMDDKLS--------ENGDQNLQQLTNMRQKMWRAFENP---HTS 181

  Fly    74 ----IFYHVMVFLMVFTCLALSVFSTI---------------KEYEEDAVYILFRMEILVVIWFT 119
                :||:|..|.:..:.:| :|..|:               :.|:    .:.|.::...|:.||
  Fly   182 TSALVFYYVTGFFIAVSVMA-NVVETVPCGHRPGRAGTLPCGERYK----IVFFCLDTACVMIFT 241

  Fly   120 MEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFF 184
            .|:..||:::.         .|.|||:....|||:|.|:...:.||:..:..|  :.|...||.|
  Fly   242 AEYLLRLFAAP---------DRCKFVRSVMSIIDVVAIMPYYIGLGITDNDDV--SGAFVTLRVF 295

  Fly   185 QILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLG-------LIFASFLVYMWEKDVN-DK 241
            ::.|:.:..|.....::||..:.:...||      |||.       :|||:.:.|. ||:|| ..
  Fly   296 RVFRIFKFSRHSQGLRILGYTLKSCASEL------GFLVFSLAMAIIIFATVMFYA-EKNVNGTN 353

  Fly   242 FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQR 306
            |::...|.|:.::|:.|:|||||||.|..||::...|:|.|:...|||..::.|.|:....|.||
  Fly   354 FTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQR 418

  Fly   307 -QKHMIRRRQPAATL-----------------IQAVWRCYAADEHSVSV---------------- 337
             .|...:|:...|.:                 .:|.|   ||.|..:.:
  Fly   419 ADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEARW---AAQESGIELDDNYRDEDIFELQHHH 480

  Fly   338 ------ATWNIHRVAL-------------PSPPASRASSSFKHNTSFVARL 369
                  .|.:...|.|             |||.||.|     |:|:..|.|
  Fly   481 LLRCLEKTTDREFVELEIPFNGQPKRPGSPSPMASPA-----HSTNSAAGL 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNQ	NP_788300.3	Ion_trans	100..305	CDD:278921	64/212 (30%)
		Ion_trans_2	221..295	CDD:285168	31/81 (38%)
		KCNQ_channel	<619..719	CDD:281513
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	4/15 (27%)
		Ion_trans	188..415	CDD:395416	70/249 (28%)
		DUF3399	445..540	CDD:403174	18/90 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840