| Sequence 1: | NP_788300.3 | Gene: | KCNQ / 36071 | FlyBaseID: | FBgn0033494 | Length: | 993 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001365898.1 | Gene: | KCND3 / 3752 | HGNCID: | 6239 | Length: | 655 | Species: | Homo sapiens |
| Alignment Length: | 544 | Identity: | 130/544 - (23%) |
|---|---|---|---|
| Similarity: | 217/544 - (39%) | Gaps: | 116/544 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 5 NDIYAFYDI----------RGYKGKCRPGRPNSERILQPRMSLLGKPLNYNRGTRRDVRYRRLQS 59
Fly 60 RLYNFLERPR--GLHAIFYHVMVFLMVFTCLALSVFSTIKEY---------------EEDAVYIL 107
Fly 108 FRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQV 172
Fly 173 FATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFL-------GLIFASFL 230
Fly 231 VYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGS 295
Fly 296 GFALKVQQQQR-------QKHMIRRRQPAAT--------------LIQAVWRCYAADEHSVSVAT 339
Fly 340 WNI---HRVALPSPPASRASSSFKHNTSFVARLPTIRRHK------------SQTIQTPGGGDGG 389
Fly 390 GVSKPPG-----SSRASTRYTRTIRDINASVENLEVVQNGKSMNPSFSED-SVAETTCLKNIKNS 448
Fly 449 DASQPATLANCKLSSSAGSLAQFP 472 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNQ | NP_788300.3 | Ion_trans | 100..305 | CDD:278921 | 63/211 (30%) |
| Ion_trans_2 | 221..295 | CDD:285168 | 28/80 (35%) | ||
| KCNQ_channel | <619..719 | CDD:281513 | |||
| KCND3 | NP_001365898.1 | Interaction with KCNIP2. /evidence=ECO:0000250 | 2..20 | ||
| BTB_POZ_KCND3 | 6..143 | CDD:349726 | 8/30 (27%) | ||
| Ion_trans | 186..412 | CDD:395416 | 69/248 (28%) | ||
| Selectivity filter. /evidence=ECO:0000250 | 367..372 | 3/4 (75%) | |||
| DUF3399 | 442..563 | CDD:403174 | 21/121 (17%) | ||
| Mediates dendritic targeting. /evidence=ECO:0000250 | 472..487 | 3/14 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 525..565 | 9/40 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 615..655 | 1/4 (25%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||