| Sequence 1: | NP_788300.3 | Gene: | KCNQ / 36071 | FlyBaseID: | FBgn0033494 | Length: | 993 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002225.2 | Gene: | KCNA5 / 3741 | HGNCID: | 6224 | Length: | 613 | Species: | Homo sapiens |
| Alignment Length: | 387 | Identity: | 93/387 - (24%) |
|---|---|---|---|
| Similarity: | 147/387 - (37%) | Gaps: | 115/387 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 DPDNDIYAFYDIRGYKGKCRPGRPNSERILQPRMS--LLGKPLN------------YNRGTRRDV 52
Fly 53 RYR----------------RLQSRLYNFLERP------RGLHAIFYHVMVFLMVFTCLALSVFST 95
Fly 96 IKEYEEDAVYI-----------------------------------------LFRMEILVVIWFT 119
Fly 120 MEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGM------------GTSG-Q 171
Fly 172 VFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEK 236
Fly 237 D-VNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGF 297 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNQ | NP_788300.3 | Ion_trans | 100..305 | CDD:278921 | 67/253 (26%) |
| Ion_trans_2 | 221..295 | CDD:285168 | 34/74 (46%) | ||
| KCNQ_channel | <619..719 | CDD:281513 | |||
| KCNA5 | NP_002225.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..108 | ||
| 2 X 11 AA tandem repeat of D-[SP]-G-V-R-P-L-P-P-L-P | 61..82 | ||||
| BTB_2 | 122..213 | CDD:308049 | 15/65 (23%) | ||
| Ion_trans | 249..526 | CDD:306908 | 73/285 (26%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 282..304 | 0/21 (0%) | |||
| S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 | 418..431 | 3/12 (25%) | |||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 480..485 | 4/4 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 532..559 | ||||
| PDZ-binding. /evidence=ECO:0000250 | 611..613 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||