| Sequence 1: | NP_788300.3 | Gene: | KCNQ / 36071 | FlyBaseID: | FBgn0033494 | Length: | 993 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032449.1 | Gene: | Kcnd1 / 16506 | MGIID: | 96671 | Length: | 651 | Species: | Mus musculus |
| Alignment Length: | 604 | Identity: | 135/604 - (22%) |
|---|---|---|---|
| Similarity: | 203/604 - (33%) | Gaps: | 227/604 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 57 LQSRLYNFLERPRGLHA--IFYHVMVFLMVFTCLALSVFSTI----------KEYE--EDAVYIL 107
Fly 108 FRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQV 172
Fly 173 FATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFL-------GLIFASFL 230
Fly 231 VYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGS 295
Fly 296 GFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIHRVALPSPPASRASSSFK 360
Fly 361 HNTSFVARLPTIRRHKSQTIQTPGGGDG------------------------------------- 388
Fly 389 --------GG--------VSKP--PGS------SRASTRYTRTIRDINASVENLEVVQNGKSMNP 429
Fly 430 SFSEDSVAETTCLKNIKNSDASQPATLANCKLSSSAGSLAQFPDRNRDRDQDRRGHGEGEGDQAE 494
Fly 495 EQAKAGGSRRNLTIPVVLYGFLHGNFLGSTLSLRNPRVAPANDRDLEAGRDEDEVHKDTCQRSNT 559
Fly 560 LPLPVKPDSPSGSPGSGRT 578 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNQ | NP_788300.3 | Ion_trans | 100..305 | CDD:278921 | 60/213 (28%) |
| Ion_trans_2 | 221..295 | CDD:285168 | 28/80 (35%) | ||
| KCNQ_channel | <619..719 | CDD:281513 | |||
| Kcnd1 | NP_032449.1 | Interaction with KCNIP2. /evidence=ECO:0000250 | 2..20 | ||
| BTB_POZ | 6..143 | CDD:365784 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 144..164 | ||||
| Ion_trans | 185..417 | CDD:395416 | 69/249 (28%) | ||
| Selectivity filter. /evidence=ECO:0000250 | 372..377 | 3/4 (75%) | |||
| DUF3399 | 447..550 | CDD:403174 | 20/133 (15%) | ||
| Mediates dendritic targeting. /evidence=ECO:0000250 | 474..489 | 0/14 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 566..585 | 6/29 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 601..651 | 14/52 (27%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||