Protein Alignment KCNQ and Kcnc1

DIOPT Version :9

• Sequence 1: NP_788300.3
• Gene: KCNQ / 36071
• FlyBaseID: FBgn0033494
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: XP_006540709.1
• Gene: Kcnc1 / 16502
• MGIID: 96667
• Length: 594
• Species: Mus musculus
• Alignment Length: 343
• Identity: 89/343 - (25%)
• Similarity: 148/343 - (43%)
• Gaps: 70/343 - (20%)

  Fly    23 GRPNSERILQPRMSLL----GKPLNYNRGTRRDVRYRRLQSRLYNFLERPRG-------LHAIFY 76
            |....|..:..|::|.    |:|..:         :||.|.|::...|.|..       ..|..:
Mouse   143 GDGEDELEMTKRLALSDSPDGRPGGF---------WRRWQPRIWALFEDPYSSRYARYVAFASLF 198

  Fly    77 HVMVFLMVFTCLALSVFSTI------------------KEYEEDAVYILFRMEILVVIWFTMEFG 123
            .::|.:..|.......|:.|                  :|.|.:|  .|..:|.:.|:|||.||
Mouse   199 FILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEA--FLTYIEGVCVVWFTFEF- 260

  Fly   124 ARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGM-GTSGQVF--ATSALRGLRFFQ 185
                    ..|...|..:::|:|....|||.|.||...:.:|: |.|.:..  ....||.:||.:
Mouse   261 --------LMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVR 317

  Fly   186 ILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEK---DVND------- 240
            |||:.::.|.....::||..:.|...|.:..:....||::..:.::|..|:   ..||
Mouse   318 ILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHT 382

  Fly   241 KFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGIL----GSGFALKV 301
            .|.|.....||.|:|:.|:|||||.|.||.|.|:.:.|||.|:...|:|..::    |..::|.:
Mouse   383 HFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAM 447

  Fly   302 QQQ----QRQKHMIRRRQ 315
            .:|    :::||:.|..|
Mouse   448 AKQKLPKKKKKHIPRPPQ 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNQ	NP_788300.3	Ion_trans	100..305	CDD:278921	67/225 (30%)
		Ion_trans_2	221..295	CDD:285168	29/87 (33%)
		KCNQ_channel	<619..719	CDD:281513
Kcnc1	XP_006540709.1	BTB_KCNC1_3	6..122	CDD:349721
		Ion_trans	189..447	CDD:366146	72/268 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810