Sequence 1: | NP_788300.3 | Gene: | KCNQ / 36071 | FlyBaseID: | FBgn0033494 | Length: | 993 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_032446.2 | Gene: | Kcnb1 / 16500 | MGIID: | 96666 | Length: | 857 | Species: | Mus musculus |
Alignment Length: | 770 | Identity: | 170/770 - (22%) |
---|---|---|---|
Similarity: | 273/770 - (35%) | Gaps: | 228/770 - (29%) |
- Green bases have known domain annotations that are detailed below.
Fly 58 QSRLYNFLERPRGLHA--IFYHVMVFLMVFTCLALSVFSTIKEYEEDAVY-------ILFRMEIL 113
Fly 114 VVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSG-------- 170
Fly 171 -----QVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFL 230
Fly 231 VYMWEKDVND-KFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILG 294
Fly 295 SGFALKVQQQQRQKHMIRRRQPA------ATLI-----------------------QAVWRCYAA 330
Fly 331 DEHSVSVATWNIHRVALPSPPASRASSSFKHNTSFVARLPTIRRHKSQTIQTPGGGDGGGVSKPP 395
Fly 396 GSSRASTRYTRTIRDINASVENL--EVVQNGKSMNPSFSEDSVAETTCLKNIKNSDASQPATLA- 457
Fly 458 ---------NCKLSSSAGSL----AQFPDRNRDRDQDRRGHGEGEGDQAEEQAKAGGSRRNLTIP 509
Fly 510 VVLY-GFLHGNFLGSTLSLRNPRVAPANDRD---LEAGRDEDEVHKDTCQRS---NTL---PLPV 564
Fly 565 KP-----DSPSGSPGSGRTGRFFAAASHFLETGFSSPNPIID-------VANEEDEPRCTQLTNR 617
Fly 618 HKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGKQGSKA 682
Fly 683 KDVYAS---KISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPK 734 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
KCNQ | NP_788300.3 | Ion_trans | 100..305 | CDD:278921 | 62/225 (28%) |
Ion_trans_2 | 221..295 | CDD:285168 | 30/74 (41%) | ||
KCNQ_channel | <619..719 | CDD:281513 | 16/102 (16%) | ||
Kcnb1 | NP_032446.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | ||
BTB_POZ_KCNB2 | 15..141 | CDD:349719 | |||
Self-association. /evidence=ECO:0000250|UniProtKB:P15387 | 59..75 | ||||
Ion_trans | 188..424 | CDD:366146 | 69/253 (27%) | ||
Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 377..382 | 4/4 (100%) | |||
Self-association. /evidence=ECO:0000250|UniProtKB:P15387 | 448..481 | 1/32 (3%) | |||
Kv2channel | 467..678 | CDD:367541 | 53/265 (20%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 475..569 | 23/130 (18%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 608..627 | 8/22 (36%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 768..802 | 9/56 (16%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 816..857 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |