DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment KCNQ and LOC101887046

DIOPT Version :9

Sequence 1:	NP_788300.3	Gene:	KCNQ / 36071	FlyBaseID:	FBgn0033494	Length:	993	Species:	Drosophila melanogaster
Sequence 2:	XP_005159814.1	Gene:	LOC101887046 / 101887046	-ID:	-	Length:	258	Species:	Danio rerio

Alignment Length:	135	Identity:	61/135 - (45%)
Similarity:	85/135 - (62%)	Gaps:	12/135 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GRPNSERILQPRMSLLGKPLNYNRGTR-----RDVRYRRLQSRLYNFLERPRGLHAIFYHVMVFL 82
            |.|:.      |..|||.||....|.|     ...|||:||:.|||.|||||| .|..||..:||
Zfish    46 GHPSH------RTGLLGTPLPVPPGPRATPSASSKRYRKLQNCLYNVLERPRG-WAFIYHAFIFL 103

  Fly    83 MVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKR 147
            :||:||.|||||||.::.:.|...||.:|.::::.|.:|:..|:|::||..||:|..|||:|.::
Zfish   104 LVFSCLVLSVFSTIPDHHKFANEALFILEFVMIVVFGLEYFVRIWAAGCCCRYRGWQGRLRFARK 168

  Fly   148 PFCII 152
            |||:|
Zfish   169 PFCVI 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KCNQ	NP_788300.3	Ion_trans	100..305	CDD:278921	21/53 (40%)
		Ion_trans_2	221..295	CDD:285168
		KCNQ_channel	<619..719	CDD:281513
LOC101887046	XP_005159814.1	KCNQ_channel	<190..216	CDD:281513
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168835at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920