Protein Alignment KCNQ and kcng4

DIOPT Version :10

• Sequence 1: NP_788300.3
• Gene: KCNQ / 36071
• FlyBaseID: FBgn0033494
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: XP_002934997.1
• Gene: kcng4 / 100497160
• XenbaseID: XB-GENE-985941
• Length: 506
• Species: Xenopus tropicalis
• Alignment Length: 292
• Identity: 79/292 - (27%)
• Similarity: 138/292 - (47%)
• Gaps: 60/292 - (20%)

  Fly    60 RLYNFLERPR-GLHA-IFYHVMVFLMVFTCLALSVFSTIKEY--EED------AVYILFRMEILV 114
            :|.:.:|.|: |:.. :|..:.:..:..|.:.|.| ||:.:.  |||      ..|.:|.:|.:.
 Frog   204 KLRDMVENPQSGIPGKVFACLSIIFVATTAINLCV-STMPDLRAEEDRGECSQMCYNIFIIETIC 267

  Fly   115 VIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTIL---ASIVV------------- 163
            |.||::||..|...:  :|:.|       |.|.|..|||::.||   .|::|
 Frog   268 VAWFSLEFFLRFIQA--KSKCQ-------FFKGPLNIIDVLAILPYYVSLIVEDEQKTVDKPSSN 323

  Fly   164 -----LGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQEL-ITTMYIGFL 222
                 :|:          .||.||..:||.::|:.|.....:.||..|....:|. :..:::...
 Frog   324 SYLEKIGL----------VLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLCVA 378

  Fly   223 GLIFASFLVYMWEKDVN--DKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISF 285
            ..:||. ||::.|.::.  .:|::...:.||.:|::.|||||||||.:..|:::|....|.||..
 Frog   379 VTLFAP-LVHLAENEMGRCQEFTSVPASYWWAIISMTTVGYGDMVPRSIPGQVVALSSILSGILI 442

  Fly   286 FALPAGILGSGFA-----LKVQQQQRQKHMIR 312
            .|.||..:...|:     ||.:|::.|..::|
 Frog   443 MAFPATSIFHTFSRCYSELKREQERLQSRLMR 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNQ	NP_788300.3	Ion_trans	72..305	CDD:459842	73/270 (27%)
		KCNQ_channel	<619..719	CDD:460954
kcng4	XP_002934997.1	BTB_POZ_KCNG4	59..170	CDD:349730
		Ion_trans	219..462	CDD:459842	70/263 (27%)