Protein Alignment KCNQ and LOC100492908

DIOPT Version :9

• Sequence 1: NP_788300.3
• Gene: KCNQ / 36071
• FlyBaseID: FBgn0033494
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: XP_031754514.1
• Gene: LOC100492908 / 100492908
• -ID: -
• Length: 671
• Species: Xenopus tropicalis
• Alignment Length: 723
• Identity: 271/723 - (37%)
• Similarity: 375/723 - (51%)
• Gaps: 164/723 - (22%)

  Fly    57 LQSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTME 121
            :|..:|||||||.|.....||..|||:|..||..||.|||:.|.|.|...||.|||::|::|..|
 Frog    85 MQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAE 149

  Fly   122 FGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQI 186
            :..||||:||||:|.|..||::|.::|..|||::.::|||:||.:|::||||||||:||:||.||
 Frog   150 YLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQI 214

  Fly   187 LRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK-----FSNFA 246
            |||:.:||:||||:||||||:.||||||||:|||||||||:|:.||:.|||..|:     ||::|
 Frog   215 LRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDEEGRTGFSSYA 279

  Fly   247 QALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMI 311
            .||||||:|:.|:||||.||.||.||.||||.::..|||||||||||||||||||||:|||||..
 Frog   280 DALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFN 344

  Fly   312 RRRQPAATLIQAVWRCYAADEHSVSVATWNIHRVALPSPPASRASSSFKHNTSFVARLPTIRRHK 376
            |:...||:|||.:||||||::...|.|||.|:.    :||                      ...
 Frog   345 RQIPAAASLIQTLWRCYAAEKSYSSTATWKIYL----TPP----------------------EQG 383

  Fly   377 SQTIQTPGGGDGGGVSKPPGSSRASTRYTRTIRDINASVENLEVVQNGKSMNPSFSEDSVAETTC 441
            ::|...|..         |.|.:.:.|..:..:.|:.:..|        .|:|      |....|
 Frog   384 NKTPMAPAS---------PTSRKQNRRCKKKSKSIHEACVN--------PMSP------VLAPLC 425

  Fly   442 LKNIKNSDASQPATLANCKLSSSAGSLAQFPDRNRDRDQDRRGHGEGEGDQAEEQAKAGGSRRNL 506
            |.....:..|.|                                        :|.|        |
 Frog   426 LSPTLRTPRSPP----------------------------------------QENA--------L 442

  Fly   507 TIPVVLY----------GFLHGNFLGSTLSLRNPRVAPANDRDLEAGRDEDEVHKDTCQRSNTLP 561
            ::|.:.|          ||            ::|           |||.........|...:..
 Frog   443 SVPHITYHHTEEDKADDGF------------QDP-----------AGRPRSWSSLSICTSFSLT- 483

  Fly   562 LPVKPDSPSGSPGSGRTGRFFAAASHFLETGFSSPNPIIDVANEEDE-PRCT-------QLTNRH 618
                      |.|.||.|:.....|.     .:|....||..:||.. |..|       :||..|
 Frog   484 ----------SQGRGRPGQSLPDISR-----TNSYTDDIDGISEESALPAVTDLSHTVSRLTEAH 533

  Fly   619 KTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGKQG--SK 681
            :.|::..|:::||||||||::|.|||||:||:|||:.||::::.|:|.|..|||..|||.|  ..
 Frog   534 RMAVKVTRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHSLGKPGLFLP 598

  Fly   682 AKDVYASKISLASRVVKVERQVADIEEKLDILI---KAYMEDRDRFLALPLPAKPKIHSISPSHK 743
            .|.|.....::.||::::|.:|..::.|||.::   :|.:...:.......|:.|..|.:.||..
 Frog   599 EKGVDKGYYTVGSRLMRLEEKVNRMDHKLDEILCVFRAQLVPEEDPAQSSQPSSPASHRLHPSPS 663

  Fly   744 PLHHAHNL 751
            ...|:..|
 Frog   664 SPTHSRKL 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNQ	NP_788300.3	Ion_trans	100..305	CDD:278921	132/209 (63%)
		Ion_trans_2	221..295	CDD:285168	49/78 (63%)
		KCNQ_channel	<619..719	CDD:281513	43/104 (41%)
LOC100492908	XP_031754514.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1168835at2759
OrthoFinder	1	1.000	-	-		FOG0003178
OrthoInspector	1	1.000	-	-		otm47876
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010