Protein Alignment KCNQ and kcna1

DIOPT Version :9

• Sequence 1: NP_788300.3
• Gene: KCNQ / 36071
• FlyBaseID: FBgn0033494
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: XP_004912857.1
• Gene: kcna1 / 100492822
• XenbaseID: XB-GENE-991584
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 110/509 - (21%)
• Similarity: 184/509 - (36%)
• Gaps: 159/509 - (31%)

  Fly     2 DPDNDIYAFYDIRGYKGKCRPGRPNSERILQPRMS--LLGKPLN------------YNRGT---- 48
            ||..:.| |:|         ..||:.:.||....|  .|.:|:|            |..|.
 Frog    71 DPLRNEY-FFD---------RNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAME 125

  Fly    49 --RRDVRYRRLQSR-------------LYNFLER--PRGLHAIFYHVMVFL--MVFTCLALSVFS 94
              |.|..:.|.:.|             |:.:.|.  |..:.|| ..|||.|  :|..||     .
 Frog   126 KFREDEGFIREEERPLPEKEFQRQVWLLFEYPESSGPARIIAI-VSVMVILISIVIFCL-----E 184

  Fly    95 TIKEYEEDAVYI------------------LFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGR 141
            |:.|.:::.::.                  .|.:|.|.:|||:.|...|.::         |..:
 Frog   185 TLPELKDERIFSRRVNNSTVFYKSNIFTDPFFVVETLCIIWFSFELVVRFFA---------CPSK 240

  Fly   142 LKFVKRPFCIIDIVTILASIVVLGMGTS--------GQVFATSALRGLRFFQILRMVRMDRRGGT 198
            .:|.|.....||||.|:...:.||...:        .|..:.:.||.:|..::.|:.::.|....
 Frog   241 PEFFKNIMNFIDIVAIIPYFITLGTEMAEQEGPQKGEQATSLAILRVIRLVRVFRIFKLSRHSKG 305

  Fly   199 WKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK-FSNFAQALWWGVITLCTVGYG 262
            .::||..:.|..:||...::..|:|:|..|..||..|.:.::. |::...|.||.|:::.|||||
 Frog   306 LQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEDESHFASIPDAFWWAVVSMTTVGYG 370

  Fly   263 DMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRC 327
            ||.|:|..||::.|.||:.|:...|||..::.|.|
 Frog   371 DMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNF------------------------------ 405

  Fly   328 YAADEHSVSVATWNIHRVALPSPPASRASSSFKHNTSFVARLPTIRRHKSQTIQTPGGGDGGGVS 392
                       .:..||     .......:...|                  :.||.......:|
 Frog   406 -----------NYFYHR-----ETEGEEQAQLLH------------------VSTPNLASDSDLS 436

  Fly   393 KPPGSSRASTRYTRTIRDINASVENLEVVQNGKSMNPSFSEDSVAETTCLKNIK 446
            :...|:.:.:.|.....|:|.|::|.      :..|......::|...|:...|
 Frog   437 RRSSSTMSKSEYMEIEEDLNNSIDNF------REANIRTGNCTIANQNCVNKSK 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNQ	NP_788300.3	Ion_trans	100..305	CDD:278921	61/231 (26%)
		Ion_trans_2	221..295	CDD:285168	30/74 (41%)
		KCNQ_channel	<619..719	CDD:281513
kcna1	XP_004912857.1	BTB_POZ	34..160	CDD:365784	21/98 (21%)
		Ion_trans	163..412	CDD:366146	74/309 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910