Protein Alignment KCNQ and si:dkey-43k4.5

DIOPT Version :10

• Sequence 1: NP_788300.3
• Gene: KCNQ / 36071
• FlyBaseID: FBgn0033494
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: XP_021332757.1
• Gene: si:dkey-43k4.5 / 100148290
• ZFINID: ZDB-GENE-120215-82
• Length: 487
• Species: Danio rerio
• Alignment Length: 296
• Identity: 69/296 - (23%)
• Similarity: 135/296 - (45%)
• Gaps: 48/296 - (16%)

  Fly    51 DVRYRRLQSRLYNFLERP-RGLHAIFYHVMVFLMVFTCLALSVFSTIKEY----------EEDAV 104
            ::|:..::..|:..||.| ..:.:..:.::...:|...:|....::|.||          |:..:
Zfish   162 EMRFGNIRKCLWLTLENPGYSIPSKLFSLLSICVVLISIATMCINSIPEYQKFDENGNLIEDPTM 226

  Fly   105 YILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVL----- 164
            ::|   |:..:.|||.|...|:..:.         ...||...|..:|||::::...:.:
Zfish   227 HVL---EVFCICWFTFEVVTRMLLAP---------NHRKFFLLPLNVIDIISVMPIYITIFFDML 279

  Fly   165 -----GMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGL 224
                 .:|..|::  ...||.:|.|::|::.|  ...|...|..::.:::|:..|..:|:. :|:
Zfish   280 IGSESELGNLGKL--VQVLRLMRIFRVLKLAR--HSTGLRSLGATLRHSYREVGILLLYLA-VGV 339

  Fly   225 IFASFLVYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALP 289
            ...|.:.|..|.:.:..........|||.:::.||||||:||:|..|||.||.|.|.|....|||
Zfish   340 SVFSGMAYTAENEEDVGLDTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGTLVVALP 404

  Fly   290 AGILGSGFA----------LKVQQQQRQKHMIRRRQ 315
            ..|:.:.|:          ..|:....:|.::|:::
Zfish   405 ITIIFNKFSHFYRKQKALEASVRNNNNKKFVMRQQR 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNQ	NP_788300.3	Ion_trans	72..305	CDD:459842	62/262 (24%)
		KCNQ_channel	<619..719	CDD:460954
si:dkey-43k4.5	XP_021332757.1	BTB_POZ	18..122	CDD:453885
		Ion_trans	185..420	CDD:459842	61/251 (24%)