Protein Alignment CG18011 and ZNF668

DIOPT Version :10

• Sequence 1: NP_610559.1
• Gene: CG18011 / 36068
• FlyBaseID: FBgn0033491
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_001166140.1
• Gene: ZNF668 / 79759
• HGNCID: 25821
• Length: 642
• Species: Homo sapiens
• Alignment Length: 642
• Identity: 134/642 - (20%)
• Similarity: 203/642 - (31%)
• Gaps: 198/642 - (30%)

  Fly   398 CPECKLTFSNILQYNKHSCAH----------VIKKKRGFRSYCEMCSLEFPSWKRFNFHSQFHLE 452
            |..|..||.|..:..:|:..|          .:|.|....:..|..|.|..|..         ..
Human    47 CLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKAEEASGEKVSGS---------AA 102

  Fly   453 KHRPRACFVCDYATTNIDELFQHLNYSHEPVGTLFCDLCDRTFRDPSVFMEHNKSHANVSSTTYS 517
            |.||.||.:|..|.....||..| ..||.......|..|.|.|..|.....|..|||  ....:.
Human   103 KPRPYACPLCPKAYKTAPELRSH-GRSHTGEKPFPCPECGRRFMQPVCLRVHLASHA--GELPFR 164

  Fly   518 CSECMANFESRGRLNGHMRAMHGS-VISCELCSREFATEATYNIHMKKHLIIEKDVHVCSTCGL- 580
            |:.|...:.:..:|..|.|...|. ..:|..|.:.||..:.:..|.:.|..:..  :.|..||.
Human   165 CAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVFRKHRRTHAGLRP--YSCERCGKA 227

  Fly   581 ---LSDSRETLLAHVNSVKTACFGSKIDVELLRDAYVCEYCSSYFKEKDCLQAHRDSGVH-KDGV 641
               |.|.|....:|.        |.:        .::|..|...|.....|..|:  .:| ....
Human   228 YAELKDLRNHERSHT--------GER--------PFLCSECGKSFSRSSSLTCHQ--RIHAAQKP 274

  Fly   642 FLCQPCGKEFPHMKLYRHHLRNYQQLRSDSTHRRLEICVYYMCDQENCTESYVNWNSLYTHKRRT 706
            :.|..|||.|..:..|:.|.|.:...:.            ::|.:  |...:.:.:|...| :|.
Human   275 YRCPACGKGFTQLSSYQSHERTHSGEKP------------FLCPR--CGRMFSDPSSFRRH-QRA 324

  Fly   707 HESASKQAEKSSKSAQEWVCQFCLKECRSKMSLSVHVARSHNNDN-VTCPLCNSSYKSHDALAKH 770
            ||           ..:.:.|:.|.|:.|....|::| .|.|..|. ..|..|:.::.:...| |.
Human   325 HE-----------GVKPYHCEKCGKDFRQPADLAMH-RRVHTGDRPFKCLQCDKTFVASWDL-KR 376

  Fly   771 HAYWH---EPIECPECFKIVKNRRNYDTHVNVVHSNKKRYSCSVCQKGFYHKSEMEAHQKLH--- 829
            ||..|   .|..|.||.:....|.:...| :.|||.::.:.|:.|.|.|...|.:..|::.|
Human   377 HALVHSGQRPFRCEECGRAFAERASLTKH-SRVHSGERPFHCNACGKSFVVSSSLRKHERTHRSS 440

  Fly   830 ----------------------GQS---------------------------------------- 832
                                  |:|
Human   441 EAAGVPPAQELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLGLPPESGGVMATQWQVVGMTVE 505

  Fly   833 ---------------------------------YSCEQCSFTTRNKKSLSVHVLGQHYKRF---- 860
                                             :.|.:|      |::.|...|.:.::|.
Human   506 HVECQDAGVREAPGPLEGAGEAGGEEADEKPPQFVCREC------KETFSTMTLLRRHERSHPEL 564

  Fly   861 -AFECNVCKKRFGRSQGLKTHMQRAHGD--KYTCRDYFDGGCGRTFVNSSQLNVHVR 914
             .|.|..|.|.|....||:.| .|.|..  .|||..     |.:.|:::|.|..|.|
Human   565 RPFPCTQCGKSFSDRAGLRKH-SRTHSSVRPYTCPH-----CPKAFLSASDLRKHER 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18011	NP_610559.1	C2H2 Zn finger	488..508	CDD:275368	6/19 (32%)
		C2H2 Zn finger	518..538	CDD:275368	5/19 (26%)
		C2H2 Zn finger	545..565	CDD:275368	5/19 (26%)
		C2H2 Zn finger	575..596	CDD:275371	7/24 (29%)
		C2H2 Zn finger	754..775	CDD:275368	6/20 (30%)
		C2H2 Zn finger	780..801	CDD:275368	5/20 (25%)
		C2H2 Zn finger	809..829	CDD:275368	6/19 (32%)
		SUF4-like	852..>891	CDD:411020	13/45 (29%)
		C2H2 Zn finger	864..885	CDD:411020	8/20 (40%)
		C2H2 Zn finger	864..885	CDD:275368	8/20 (40%)
		C2H2 Zn finger	891..917	CDD:275368	7/24 (29%)
ZNF668	NP_001166140.1	COG5048	103..437	CDD:227381	93/385 (24%)
		C2H2 Zn finger	109..129	CDD:275370	6/20 (30%)
		C2H2 Zn finger	137..157	CDD:275368	6/19 (32%)
		C2H2 Zn finger	165..185	CDD:275368	5/19 (26%)
		C2H2 Zn finger	193..213	CDD:275368	5/19 (26%)
		C2H2 Zn finger	221..241	CDD:275368	6/19 (32%)
		C2H2 Zn finger	249..269	CDD:275368	5/21 (24%)
		COG5048	271..618	CDD:227381	74/386 (19%)
		C2H2 Zn finger	277..297	CDD:275368	8/19 (42%)
		C2H2 Zn finger	305..325	CDD:275368	5/22 (23%)
		C2H2 Zn finger	333..353	CDD:275368	7/20 (35%)
		C2H2 Zn finger	361..381	CDD:275368	6/20 (30%)
		C2H2 Zn finger	389..409	CDD:275368	5/20 (25%)
		C2H2 Zn finger	417..437	CDD:275368	6/19 (32%)
		C2H2 Zn finger	541..561	CDD:275368	6/25 (24%)
		C2H2 Zn finger	569..589	CDD:275368	8/20 (40%)
		C2H2 Zn finger	597..617	CDD:275368	7/24 (29%)