Protein Alignment CG18011 and znf271

DIOPT Version :10

• Sequence 1: NP_610559.1
• Gene: CG18011 / 36068
• FlyBaseID: FBgn0033491
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: XP_073797464.1
• Gene: znf271 / 793549
• ZFINID: ZDB-GENE-091204-74
• Length: 1097
• Species: Danio rerio
• Alignment Length: 1176
• Identity: 260/1176 - (22%)
• Similarity: 392/1176 - (33%)
• Gaps: 354/1176 - (30%)

  Fly     1 MSENAKNNSCLHCSVFSTKYQYQEIFDEFGIELGLQSLLSRHYQLEVSPDP-------------- 51
            :|...|...|..|....::.|:                ||.|.::.....|
Zfish    59 LSATVKPFQCSQCGKGFSRIQH----------------LSEHVRIHTGERPFQCLECGKTFARER 107

  Fly    52 --QKQQLL--------CEVCVTNLIRLFDIDELEREREAAKDAAQGKDSKAEEDPIIITEVQATP 106
              :..||:        |.:||.|...|   ..|:|...|..   ||:|...|...:|..|
Zfish   108 DLKTHQLVHTDAKAFHCVICVKNFALL---SSLKRHLRAFH---QGEDVSTEGKCLICVE----- 161

  Fly   107 PAAKPAKKTVPSRPLTKVLRPVPIIPTREPSARIRNRAAAASNVTPDTSRSPEPPETPSTEDAVS 171
             ..|.....:....||.             :..|.:|.....|...|.|......:|.|..|.|.
Zfish   162 -CGKNFDCDLEEHELTH-------------TGEISHRCPDCVNSFSDPSNLTSHDQTFSESDHVH 212

  Fly   172 KSEP--------KLVSKVADQEHFSVLIQNILDEEEAV-----VEDETAVKEESSEAVQVTEETE 223
            ..|.        .|.|:..|: |......|...|.::|     :|.:..  .|||..:|:.|...
Zfish   213 HLEDNDNERPCGSLASEDVDR-HLQTDPLNDCGEAQSVEFADNIESDGF--NESSAQIQLEEAER 274

  Fly   224 A--PGQIVILNSEAVTDTNPDENVYIYEHEDVMDPNLDNVKVKPISCS---SRLVAQAEESQSDD 283
            |  |.....|:| |..||.|.   |....|:.......:.:.||..|:   .|...||:
Zfish   275 AASPSSEHSLDS-AQKDTGPG---YAPPDEEFTADQQSSDEEKPYQCNHCEKRFNKQAK------ 329

  Fly   284 DIDEGETSNVVLFNFVDIKEKDEVDNIPEYLATVVKTSFEKLTFQWCTVC-KHCSLKCPTFESLF 347
                                          |...::....:..:| |:.| ||.|...    :|.
Zfish   330 ------------------------------LRIHLRVHTGEKPYQ-CSQCGKHFSQDV----NLK 359

  Fly   348 SHLSKAHKSRRDVYECPIEGCNKELKGRKFLAMHLVLLH---APVAEIPIYGSCPECKLTFSNIL 409
            .|. :.|.:....|:|.|  |:::......|..|..:.|   ..|||...: :||.|...|....
Zfish   360 KHY-RTHHTEEKPYQCMI--CDRKFSVSFSLIKHQRVAHPECLSVAERKRF-TCPFCGKIFGRHQ 420

  Fly   410 QYNKHSCAHVIKKKRGFRSYCEMCSLEFPSWKRFNFHSQFHLEKHRPRACFVCDYATTNIDELFQ 474
            ...:|...|.  .:|.||  |.:|:..|........|.:.|..: :|..||||........:|..
Zfish   421 DMEQHKRTHT--DERPFR--CNVCNKSFRQRSVLIVHRKIHTGE-KPFECFVCCRRFYGSGDLKT 480

  Fly   475 HLNYSHEPVGTLFCDLCDRTFRDPSVFMEHNKSHAN---------------------VSSTTYSC 518
            |:. :|..:....|.||.::|..||....|..||.|                     .|.::...
Zfish   481 HMG-THTGIRPHSCPLCSKSFPRPSSLQAHMLSHVNKQQDRNDGGFPQEEELEDACGASGSSAML 544

  Fly   519 SECM--------------------ANFESRGRLNGHMRAMHGSVISCELCSREFATEATYNIHMK 563
            ||..                    ||..|...|..|.:...     |.:|.:.||...:    ::
Zfish   545 SEDKTSNQSETGMDLSLSANQDHDANPSSSSELPDHQKPYF-----CIICGKTFALATS----LR 600

  Fly   564 KH-LIIEKDVHV--------CSTCGLLSDSRETLLAHVNSVKTACFGSKIDVELLRDAYVCEYCS 619
            || ||...|.||        ||.||.....|:.||.| ..:.|   |.:        .:.|..|:
Zfish   601 KHQLIFHPDQHVDVEGKCFACSYCGRKFGRRQGLLQH-ERIHT---GER--------PFNCPTCN 653

  Fly   620 SYFKEKDCLQAHRDSGVHK-DGVFLCQPCGKEFPHMKLYRHHLRNYQQLRSDSTHRRLEICVYYM 683
            ..|:::..|..|..|  |. :..|:|..|.|.|......:.||..:..:|..:       |..
Zfish   654 KSFRQRSALVVHIRS--HTGERAFVCFVCNKSFYTPGDLKKHLEIHTGVRPHN-------CPI-- 707

  Fly   684 CDQENCTESYVNWNSLYTHKRRTHE--SASKQ------AEKSSKSAQE--WVCQFCLK----ECR 734
                 |::.:...:.|.|| .||||  ||.||      |.|...|:||  :.|..|.|    :|.
Zfish   708 -----CSKGFGRPSFLRTH-MRTHEKTSAKKQSGSENAAGKPKASSQEKPFECSHCGKKFSQQCM 766

  Fly   735 SKMSLSVHVAR-----------------------SHNNDN-VTCPLCNSSYKSHDALAKHHAYWH 775
            .|:...:|...                       :|...| :.|.:|:.::.|..|:..|...:|
Zfish   767 FKIHQRIHTTEKRYKCTECGLSFRWRRNLISHQSTHPGQNPLQCSMCDQTFISEAAVKSHQDTFH 831

  Fly   776 EPIE--CPECFKIVKNRRNYDTHVNVVHSNKKRYSCSVCQKGFYHKSEMEAHQKLH-----GQSY 833
            ..:.  |..|.|..........||..||..::.:.|:.|.:||...|::..||:.|     .|.:
Zfish   832 SGVSHTCSLCLKTFTKSAGLRKHVRYVHEGERPHKCTECNRGFVKVSDLARHQRRHHYDRGNQLF 896

  Fly   834 SCEQCSFTTRNKKSLSVH----------------VLGQ----------HYKRF--AFECNVCKKR 870
            .|.:|..:..:..||.:|                :..|          |.|..  .|||..|.|.
Zfish   897 QCSECERSFSHPSSLVLHRRTHTEEKHQCPQCDKIFNQAGHLKVHMRTHTKEIKPKFECPDCGKS 961

  Fly   871 FGRSQGLKTHMQRAH-GDK-YTCRDYFDGGCGRTFVNSSQLNVHVRKIHDGIILLQEDVVEEDEY 933
            ||:::.|..| ||.| |:| |.|..     |.:::...:.|:||:|. |.|          |..|
Zfish   962 FGQTKDLMVH-QRVHTGEKPYQCPQ-----CKKSYRQFAHLSVHLRS-HTG----------EKPY 1009

  Fly   934 -----ITDDAPSTSKKRRL--------------NENNEFIEEADGDDIVMEDDDE-----EADDF 974
                 :...|.|:|.|:.|              ..:|..:|..  .:.|..|:||     |.:||
Zfish  1010 QCPICLKFFAHSSSMKKHLRVMHPDAKDAPVGAGPSNTSVEVK--QEPVSSDEDEFQVKSEENDF 1072

  Fly   975 --IDEI 978
              :||:
Zfish  1073 AIMDEV 1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18011	NP_610559.1	C2H2 Zn finger	488..508	CDD:275368	7/19 (37%)
		C2H2 Zn finger	518..538	CDD:275368	7/39 (18%)
		C2H2 Zn finger	545..565	CDD:275368	4/19 (21%)
		C2H2 Zn finger	575..596	CDD:275371	8/20 (40%)
		C2H2 Zn finger	754..775	CDD:275368	5/20 (25%)
		C2H2 Zn finger	780..801	CDD:275368	5/20 (25%)
		C2H2 Zn finger	809..829	CDD:275368	7/19 (37%)
		SUF4-like	852..>891	CDD:411020	18/52 (35%)
		C2H2 Zn finger	864..885	CDD:411020	9/20 (45%)
		C2H2 Zn finger	864..885	CDD:275368	9/20 (45%)
		C2H2 Zn finger	891..917	CDD:275368	6/25 (24%)
znf271	XP_073797464.1	None