Protein Alignment CG18011 and ZNF689

DIOPT Version :10

• Sequence 1: NP_610559.1
• Gene: CG18011 / 36068
• FlyBaseID: FBgn0033491
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_612456.1
• Gene: ZNF689 / 115509
• HGNCID: 25173
• Length: 500
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 94/381 - (24%)
• Similarity: 141/381 - (37%)
• Gaps: 97/381 - (25%)

  Fly   574 VCSTCGLLSDSRETLLAHVNSVKTACFGSKIDVELLRDAYVCEYCSSYFKEKDCLQAHR--DSGV 636
            :|..||......:.|.:|      .|      .:.|:..|.|..|...|.....|.:||  .||
Human   150 ICPDCGCTFPDHQALESH------KC------AQNLKKPYPCPDCGRRFSYPSLLVSHRRAHSG- 201

  Fly   637 HKDGVFLCQPCGKEFPHMKLYRHHLRNYQQLRSDSTHRRLEICVYYMCDQENCTESYVNWNSLYT 701
              :..::|..|||.|..    |.:|..:|.:.:....        |.|  .:|...:....||..
Human   202 --ECPYVCDQCGKRFSQ----RKNLSQHQVIHTGEKP--------YHC--PDCGRCFRRSRSLAN 250

  Fly   702 HKRRTHESASKQAEKSSKSAQEWVCQFCLKECRSKMSLSVHVARSHNNDN-VTCPLCNSSYKSHD 765
            | |.||     ..||..:      |..|.:.......|::| .|:|..:. .||..||..::...
Human   251 H-RTTH-----TGEKPHQ------CPSCGRRFAYPSLLAIH-QRTHTGEKPYTCLECNRRFRQRT 302

  Fly   766 ALAKHHAY--WHEPIECPEC-------FKIVKNRRNYDTHVNVVHSNKKRYSCSVCQKGFYHKSE 821
            ||..|...  ..:|..||:|       .::|.:||        |||.::.|:|..|:..|..:|.
Human   303 ALVIHQRIHTGEKPYPCPDCERRFSSSSRLVSHRR--------VHSGERPYACEHCEARFSQRST 359

  Fly   822 MEAHQKLH-GQS-YSCEQCSFTTRNKKSLSVH-----------------------VLGQHYKRFA 861
            :..||.|| |:. |.|..|....|...||::|                       :|..|.:..:
Human   360 LLQHQLLHTGEKPYPCPDCGRAFRRSGSLAIHRSTHTEEKLHACDDCGRRFAYPSLLASHRRVHS 424

  Fly   862 ----FECNVCKKRFGRSQGLKTHMQRAHGDK-YTCRDYFDGGCGRTFVNSSQLNVH 912
                :.|::|.|||.:...|..|.....|:| :.|.:     |||.|.....|.||
Human   425 GERPYACDLCSKRFAQWSHLAQHQLLHTGEKPFPCLE-----CGRCFRQRWSLAVH 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18011	NP_610559.1	C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	518..538	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	575..596	CDD:275371	5/20 (25%)
		C2H2 Zn finger	754..775	CDD:275368	6/22 (27%)
		C2H2 Zn finger	780..801	CDD:275368	6/27 (22%)
		C2H2 Zn finger	809..829	CDD:275368	6/19 (32%)
		SUF4-like	852..>891	CDD:411020	11/43 (26%)
		C2H2 Zn finger	864..885	CDD:411020	7/20 (35%)
		C2H2 Zn finger	864..885	CDD:275368	7/20 (35%)
		C2H2 Zn finger	891..917	CDD:275368	8/22 (36%)
ZNF689	NP_612456.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		KRAB	29..88	CDD:214630
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..146
		C2H2 Zn finger	151..171	CDD:275368	6/31 (19%)
		COG5048	159..>466	CDD:227381	87/361 (24%)
		C2H2 Zn finger	179..199	CDD:275368	6/19 (32%)
		C2H2 Zn finger	207..227	CDD:275368	8/23 (35%)
		C2H2 Zn finger	235..255	CDD:275368	6/22 (27%)
		C2H2 Zn finger	263..283	CDD:275368	5/20 (25%)
		C2H2 Zn finger	291..311	CDD:275368	6/19 (32%)
		C2H2 Zn finger	319..339	CDD:275368	6/27 (22%)
		C2H2 Zn finger	347..367	CDD:275368	6/19 (32%)
		C2H2 Zn finger	375..395	CDD:275368	6/19 (32%)
		C2H2 Zn finger	403..423	CDD:275368	2/19 (11%)
		C2H2 Zn finger	431..451	CDD:275368	7/19 (37%)
		C2H2 Zn finger	459..475	CDD:275368	6/20 (30%)