DRSC/TRiP Functional Genomics Resources

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Protein Alignment gem and grhl2a

DIOPT Version :9

Sequence 1:NP_610556.1 Gene:gem / 36064 FlyBaseID:FBgn0050011 Length:932 Species:Drosophila melanogaster
Sequence 2:NP_001313462.1 Gene:grhl2a / 555744 ZFINID:ZDB-GENE-050913-123 Length:593 Species:Danio rerio


Alignment Length:431 Identity:103/431 - (23%)
Similarity:166/431 - (38%) Gaps:142/431 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   378 DPAKIEIGSANGA---THAED--HKFQYILAAATSIATKNNEETLTYLNQGQSYEIKLKKIGDLS 437
            ||.:..:.:...|   ||.:.  :.|||.:.|:.|:..|..:..:.|||:||.|.|.|.:.|...
Zfish   196 DPMRYRVPTTPAAEDFTHEQAGLNMFQYNIEASRSVREKAADGPMVYLNKGQFYGITLSETGANK 260

  Fly   438 LYRDKI--LKSVIKICFHERRLQFMEREQMQQW-----QQSRPGERIIEV-DVPLSYGLCHVSQP 494
            ..|..|  :::|:.:.|.:.:.:   .||::.|     :|....:|:::: |...|:......:.
Zfish   261 GLRHPISKVRTVVMVVFGQEKCR---DEQLKHWNYWHTRQHTAKQRVLDIADYKESFNTIGNIEE 322

  Fly   495 LSSGSLNTVEIFWDPLKEVGVYIKVNCISTEFTPKKHGGEKGVPFRLQIETYIENTNSATASGSG 559
            :   :.|.|...||..:|..|:|.|||:||:|:.:|  |.||:|..:||:||..|..|       
Zfish   323 I---AYNAVSFTWDVNEEAKVFITVNCLSTDFSSQK--GVKGLPLMIQIDTYSYNNRS------- 375

  Fly   560 GSNNSAIASGSGSSGSAAPASPERTPSAGSNGKQAVHAAACQIKVFKLKGADRK-----HKQDRE 619
                                            .:.:|.|..|||||..|||:||     .||.|:
Zfish   376 --------------------------------NRPIHRAYAQIKVFCDKGAERKIRDEEKKQLRK 408

  Fly   620 KIQ---------------------KRP-----------QSEQEKFQPSYECTIMNDISLDLVMSA 652
            |::                     |||           :|:...|.|        |:.|:.:..|
Zfish   409 KVKGQTVGGHGQDGKRGNLASLPPKRPDITLFKAMTDLESQPVLFIP--------DVHLNNLQRA 465

  Fly   653 TTTGCYSPEYMKLWPNSPVHIPKYDGMLPFAPSAA-SPATSSS-------------PIAINSVTS 703
            .....:..|.|:   |..|.:.:     ||..|.| ||.|..|             ...:.....
Zfish   466 GQVFSFGVEEME---NDGVAVKR-----PFGTSEADSPPTKYSREERKVLLYVRREADEVFDALM 522

  Fly   704 TNSPTLK-LMDATN--------------MVSPQHVPADMDD 729
            ..||||| |::|.:              ..|.:.:..:|||
Zfish   523 LRSPTLKSLLEAISGKYSVPVEKMTKIYKKSKKGILVNMDD 563

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gemNP_610556.1 CP2 393..624 CDD:282385 66/266 (25%)
SAM_CP2-like 739..805 CDD:188936
grhl2aNP_001313462.1 CP2 201..411 CDD:282385 69/256 (27%)
MIEAP 441..>515 CDD:292645 18/89 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170577680
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.840

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