Protein Alignment gem and grh

DIOPT Version :9

• Sequence 1: NP_610556.1
• Gene: gem / 36064
• FlyBaseID: FBgn0050011
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_476845.2
• Gene: grh / 37038
• FlyBaseID: FBgn0259211
• Length: 1333
• Species: Drosophila melanogaster
• Alignment Length: 1121
• Identity: 227/1121 - (20%)
• Similarity: 369/1121 - (32%)
• Gaps: 437/1121 - (38%)

  Fly     3 LSFLSQN-------------------SGLLDLQSIFDPQYTHHQQQQQQLLHLSHHPQHHIQQHQ 48
            :|.||||                   :|::...:|     :||||||||            ||.|
  Fly   427 VSGLSQNEIQGFLLGSHPSSSATVSTTGVVSTTTI-----SHHQQQQQQ------------QQQQ 474

  Fly    49 NQQLQQQAEQIQQH------------------------QQERTLSTKFDLNLFNELDQMEFNNLN 89
            .||.|||.:|.|||                        ||::.:|.|      .|.:.:
  Fly   475 QQQQQQQHQQQQQHPGDIVSAAGVGSTGSIVSSAAQQQQQQQLISIK------REPEDL------ 527

  Fly    90 RSQYQNNNNNNSISNNQNSNNNTNTTNGISENLNQIQNRHFISGYHHQHIGSDYEQVINFVDSPP 154
                :.:..|.:|:       ...|.||                     .||...|.|..||:|.
  Fly   528 ----RKDPKNGNIA-------GAATANG---------------------PGSVITQKILHVDAPT 560

  Fly   155 NSE--ESWTESSSL-----IEQITIVVDGQSKDSPGPQIIDVQTIYLNSGSRKRRMDWDSLDIGQ 212
            .||  ...|.|||:     .|..:..|.|....|||.:......:|..:|..:..:        |
  Fly   561 ASEADRPSTPSSSINSTENTESDSQSVSGSESGSPGARTTATLEMYATTGGTQIYL--------Q 617

  Fly   213 SENSPTASQSGDLPSKVAHQEKEKHKREKHSGRSSWSDDIGFDLNAEFNS-NSYLNNENFLSFS- 275
            :.:..|||.:|.                 .:|.:..:...|..:.|:..| ..|:...::..::
  Fly   618 TSHPSTASGAGG-----------------GAGPAGAAGGGGVSMQAQSPSPGPYITANDYGMYTA 665

  Fly   276 --------PT-LTTLKQEP------------------QTDQIKPSPKVSLDN------------A 301
                    || .||...||                  .|..:.....||:..            .
  Fly   666 SRLPPGPPPTSTTTFIAEPSYYREYFAPDGQGGYVPASTRSLYGDVDVSVSQPGGVVTYEGRFAG 730

  Fly   302 SASPSIAIAKLDEV--------------------QNSPSQAISGQDSANGSG---------SAAN 337
            |..|......|..|                    |:...|....||..:..|         :||.
  Fly   731 SVPPPATTTVLTSVHHHQQQQQQQQQHQQQQQQQQHHQQQQHHSQDGKSNGGATPLYAKAITAAG 795

  Fly   338 GKHDV---NSGLACGCGSPQGSPLANAEYELNEKGKPQQL------------------------- 374
            ...|:   :||:.....:|:........::..|..:|..|
  Fly   796 LTVDLPSPDSGIGTDAITPRDQTNIQQSFDYTELCQPGTLIDANGSIPVSVNSIQQRTAVHGSQN 860

  Fly   375 ----SVLDPAKIEIGSANGATHAED-HK--------------------FQYILAAATSIATKNNE 414
                |::|.      |.||:|.:.. |.                    |:|.|.:..|.:.:..:
  Fly   861 SPTTSLVDT------STNGSTRSRPWHDFGRQNDADKIQIPKIFTNVGFRYHLESPISSSQRRED 919

  Fly   415 ETLTYLNQGQSYEIKLKKIGDLSL-YRDKILKSVIKICFHERRLQFMEREQMQQWQ-----QSRP 473
            :.:||:|:||.|.|.|:.:.|... .::..:||||.:.|.|.:   ...::::.||     |...
  Fly   920 DRITYINKGQFYGITLEYVHDAEKPIKNTTVKSVIMLMFREEK---SPEDEIKAWQFWHSRQHSV 981

  Fly   474 GERIIEVDVPLSYGLCHVSQPLSSGSLNTVEIFWDPLK-EVGVYIKVNCISTEFTPKKHGGEKGV 537
            .:||::.|...|.||....:.:|.   |.:.::|:||: ...:.|.|.|:||:|:.:|  |.||:
  Fly   982 KQRILDADTKNSVGLVGCIEEVSH---NAIAVYWNPLESSAKINIAVQCLSTDFSSQK--GVKGL 1041

  Fly   538 PFRLQIETYIENTNSATASGSGGSNNSAIASGSGSSGSAAPASPERTPSAGSNGKQAVHAAACQI 602
            |..:||:|:.:..::|                                        ..|...|||
  Fly  1042 PLHVQIDTFEDPRDTA----------------------------------------VFHRGYCQI 1066

  Fly   603 KVFKLKGADRKHKQDREKIQKRPQSE--QEKFQPSY-------ECTIMNDISLDLVMSATTTGCY 658
            |||..|||:||.:.:..:..||..:.  ::|....|       |...|.|.:...|:       :
  Fly  1067 KVFCDKGAERKTRDEERRAAKRKMTATGRKKLDELYHPVTDRSEFYGMQDFAKPPVL-------F 1124

  Fly   659 SP-EYMKLWPNSPVHIPKYDGMLPFAPSAASPATSSSPIAINSV--TSTNSPTLK-----LMDAT 715
            || |.|:  ....:.|....|| .|.|.:...:.|:|..::.|.  ..|:||.||     |:...
  Fly  1125 SPAEDME--KVGQLGIGAATGM-TFNPLSNGNSNSNSHSSLQSFYGHETDSPDLKGASPFLLHGQ 1186

  Fly   716 NMVSP-----QHVPADMD-DYSQNIMPESTPSQVTQWLTNHRLTAYLSTFAQFSGADIMRMSKED 774
            .:.:|     .|.|.||. |...:|:.::       .||:..||.:        |..:.|.
  Fly  1187 KVATPTLKFHNHFPPDMQTDKKDHILDQN-------MLTSTPLTDF--------GPPMKRG---- 1232

  Fly   775 LIQICGLADGIRMFNILRAKTIAPRLTLYASVDGCSYNAIYLLSNTAKELQQKLFKMPGFYEFMA 839
                       ||     ....:.|:.||...:.             :|:...|..:|
  Fly  1233 -----------RM-----TPPTSERVMLYVRQEN-------------EEVYTPLHVVP------- 1261

  Fly   840 KASAQENGAGGAATAAAAALFNNWGMHSKYSGSGSNIFNDANKSCVYISGPSGILVTITDEVLN- 903
                          .....|.|  .:.:||..|.::|.|      :|.:...||...|.|::::
  Fly  1262 --------------PTTIGLLN--AIENKYKISTTSINN------IYRTNKKGITAKIDDDMISF 1304

  Fly   904 --NEIKDGSLYALEVQ 917
              ||    .::.||||
  Fly  1305 YCNE----DIFLLEVQ 1316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gem	NP_610556.1	CP2	393..624	CDD:282385	61/258 (24%)
		SAM_CP2-like	739..805	CDD:188936	11/65 (17%)
grh	NP_476845.2	CP2	903..1089	CDD:282385	61/233 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11037
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010