Protein Alignment gem and Tfcp2l1

DIOPT Version :10

• Sequence 1: NP_610556.1
• Gene: gem / 36064
• FlyBaseID: FBgn0050011
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_001100640.1
• Gene: Tfcp2l1 / 304741
• RGDID: 1305456
• Length: 479
• Species: Rattus norvegicus
• Alignment Length: 579
• Identity: 202/579 - (34%)
• Similarity: 290/579 - (50%)
• Gaps: 156/579 - (26%)

  Fly   374 LSVLDPAKIEIGSANGATHAEDHKFQYILAAATSIATKNNEETLTYLNQGQSYEIKL---KKIGD 435
            |.:....:.::...|||...   ..||:|.||||.|.|.:|||||||||||||||:|   :|:||
  Rat    26 LPIFKQEEPQLSPENGARLP---PLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGD 87

  Fly   436 LSLYRDKILKSVIKICFHERRLQFMEREQMQQWQQSRPGERIIEVDVPLSYGLCHVSQPLSSGSL 500
            ......|.:||:|::.||:||||:.|.:|::.|:.||||:||:::|:|||.|:  :....|...|
  Rat    88 FQDLNTKYVKSIIRVVFHDRRLQYTEYQQLEGWRWSRPGDRILDIDIPLSVGI--LDPRASPTQL 150

  Fly   501 NTVEIFWDPLKEVGVYIKVNCISTEFTPKKHGGEKGVPFRLQIETYIENTNSATASGSGGSNNSA 565
            |.||..|||.|....:|:|:||||||||:|||||||||||:||:|:.:|.|.
  Rat   151 NAVEFLWDPAKRASAFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENG------------- 202

  Fly   566 IASGSGSSGSAAPASPERTPSAGSNGKQAVHAAACQIKVFKLKGADRKHKQDREKIQKRPQSEQE 630
                            |.|        :.:|:|:|||||||.||||||.|.||||::||...|:|
  Rat   203 ----------------EYT--------EHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQEKE 243

  Fly   631 KFQPSYECTIMNDISLDLVMSATTTGCYSPEYMKLWPNSPVHIPKYDGMLPFAPSAASPATSSSP 695
            |:|||||.||:             |.| ||     ||:.|..          |.|..||:.:.||
  Rat   244 KYQPSYETTIL-------------TEC-SP-----WPDVPYQ----------ANSTPSPSYNGSP 279

  Fly   696 IAINSVTSTNSPTLKLMDATNMVSPQHVPADMDDYSQNIMPESTPSQVTQWLTNHRLTAYLSTFA 760
            .:. .:...||            ||.|....:...|.:::|.::.....|||..:|.:.:...||
  Rat   280 SSF-GLREGNS------------SPNHPVEPLPLGSDHLLPSASIQDAQQWLHRNRFSQFCWLFA 331

  Fly   761 QFSGADIMRMSKEDLIQICGLADGIRMFNILRAKTIAPRLTLYA---------------SVDG-- 808
            .|||||:::||::||:|:||.|||||:||.::.:.:.|::|:|.               ..:|
  Rat   332 SFSGADLLKMSRDDLVQVCGPADGIRLFNAIKGRNVRPKMTIYVCQELEQNQLPLPQKHDENGDN 396

  Fly   809 --CSYNAIYLLSNTAKELQQKLFKMPGFYEFMAKASAQENGAGGAATAAAAALFNNWGMHSKYSG 871
              |.|:||:|...|..||.:|:                                     .|.||.
  Rat   397 SLCVYHAIFLEELTTLELTEKI-------------------------------------ASLYSI 424

  Fly   872 SGSNIFNDANKSCVYISGPSGILVTITDEVLNNEIKDGSLYALEVQAGK------VILK 924
            ...:|..      ||..||:||.|.:::|::.| .:|.|.:.|.....:      :|||
  Rat   425 PPQHIHR------VYRQGPAGIHVVVSNEMVQN-FQDESCFILSTLKAESNDGYHIILK 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gem	NP_610556.1	CP2	393..627	CDD:461338	111/236 (47%)
		SAM_CP2-like	739..805	CDD:188936	28/80 (35%)
Tfcp2l1	NP_001100640.1	CP2	35..237	CDD:461338	112/243 (46%)
		SAM_LBP9	310..376	CDD:188989	28/65 (43%)