Protein Alignment gem and Ubp1

DIOPT Version :9

• Sequence 1: NP_610556.1
• Gene: gem / 36064
• FlyBaseID: FBgn0050011
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_006244024.2
• Gene: Ubp1 / 301038
• RGDID: 1564700
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 700
• Identity: 223/700 - (31%)
• Similarity: 337/700 - (48%)
• Gaps: 207/700 - (29%)

  Fly   275 SPTLTTLKQEPQTDQIK----PSPKVSLDNASASPSIA----------IAKLDEVQNSPSQAISG 325
            ||....|...|.:.:.:    |||:      :..|..|          :..:|||..
  Rat    51 SPRRRRLHPRPPSGRARGARAPSPR------TRRPRCAGRRRGRKMAWVLSMDEVIE-------- 101

  Fly   326 QDSANGSGSAANGKHDVNSGLACGCGSPQGSPLANAEYELNEKGKPQQLSVLDPAKIEIGSANGA 390
                  ||..    ||.:|.|: |.|...|:    ..|.:::      :..|...|.|..|.:..
  Rat   102 ------SGLV----HDFDSSLS-GIGQELGA----GAYSMSD------VLALPIFKQEDSSLSLE 145

  Fly   391 THAEDHKFQYILAAATSIATKNNEETLTYLNQGQSYEIKL---KKIGDLSLYRDKILKSVIKICF 452
            ..|:...|||::.||||.|.|.::||||||||||||||::   :|:||:.....|::||:|::.|
  Rat   146 AEAKHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDVPEISGKLVKSIIRVVF 210

  Fly   453 HERRLQFMEREQMQQWQQSRPGERIIEVDVPLSYGLCHVSQPLSSGSLNTVEIFWDPLKEVGVYI 517
            |:||||:.|.:|::.|:.:|||:|::::|:|:|.|:  :....:...||.||..|||.|....:|
  Rat   211 HDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGI--IDTRTNPSQLNAVEFLWDPAKRTSAFI 273

  Fly   518 KVNCISTEFTPKKHGGEKGVPFRLQIETYIENTNSATASGSGGSNNSAIASGSGSSGSAAPASPE 582
            :|:||||||||:|||||||||||:|::|:.:|.|.                             |
  Rat   274 QVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENG-----------------------------E 309

  Fly   583 RTPSAGSNGKQAVHAAACQIKVFKLKGADRKHKQDREKIQKRPQSEQEKFQPSYECTIMNDISLD 647
            .|        ..:|:|:|||||||.||||||.|.||||::||...|:||:||||:.||:
  Rat   310 YT--------DHLHSASCQIKVFKPKGADRKQKNDREKMEKRTAHEKEKYQPSYDTTIL------ 360

  Fly   648 LVMSATTTGCYSPEYMKLWPNSPVHIPKYDGMLPFAPSAASPATSSSPIAINSVTSTNSPTLKLM 712
                   |.| ||     ||::|.         .:..::.|||.        :.||:...|..:.
  Rat   361 -------TEC-SP-----WPDTPT---------AYVNNSPSPAP--------TFTSSQQSTCSVP 395

  Fly   713 DATNMVSPQHVPADMDDYS-QNIMPESTPSQVTQWLTNHRLTAYLSTFAQFSGADIMRMSKEDLI 776
            | :|..||.|....:...| :.|.|.:|..:..|||..:|.::|...|:.|||||:::::||||:
  Rat   396 D-SNSSSPNHQGDGVAQASGEQIQPSATTQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLV 459

  Fly   777 QICGLADGIRMFNILRAKTIAPRLTLY----------------ASVDG--------CSYNAIYLL 817
            ||||.|||||::|.|:::::.||||:|                |:..|        |.|:||||.
  Rat   460 QICGAADGIRLYNSLKSRSVRPRLTIYVCQEQPSSAVPQGQPQAAGSGGEGGAGTPCVYHAIYLE 524

  Fly   818 SNTAKELQQKLFKMPGFYEFMAKASAQENGAGGAATAAAAALFNNWGMHSKYSGSGSNIFNDANK 882
            ...|.|:.:||                            |::||             ..|:..|:
  Rat   525 EMVASEVARKL----------------------------ASVFN-------------IPFHQINQ 548

  Fly   883 SCVYISGPSGILVTITDEVLNNEIKDGSLYALEVQAGKVILKLINKQDNN 932
              ||..||:||.:.::|:::.| .:|.|.:.....          |.:||
  Rat   549 --VYRQGPTGIHILVSDQMVQN-FQDESCFLFSTV----------KAENN 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gem	NP_610556.1	CP2	393..624	CDD:282385	103/233 (44%)
		SAM_CP2-like	739..805	CDD:188936	32/81 (40%)
Ubp1	XP_006244024.2	CP2	139..343	CDD:398291	104/242 (43%)
		SAM_LBP1	422..488	CDD:188987	32/65 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338249
Domainoid	1	1.000	183	1.000	Domainoid score	I3339
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	318	1.000	Inparanoid score	I2457
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001863
OrthoInspector	1	1.000	-	-		otm44722
orthoMCL	1	0.900	-	-		OOG6_104886
Panther	1	1.100	-	-	LDO	PTHR11037
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1220
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.890