Protein Alignment gem and GRHL1

DIOPT Version :9

• Sequence 1: NP_610556.1
• Gene: gem / 36064
• FlyBaseID: FBgn0050011
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_006711945.1
• Gene: GRHL1 / 29841
• HGNCID: 17923
• Length: 630
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 80/297 - (26%)
• Similarity: 127/297 - (42%)
• Gaps: 76/297 - (25%)

  Fly   371 PQQLSVLDPAKIEIGSANGATHAEDH--------KFQYILAAATSIATKNNEETLTYLNQGQSYE 427
            |..||:..|          ..::||:        .|:|.|.|:.|:..|..:.|:||||:||.|.
Human   227 PSDLSLRMP----------GMNSEDYVFDSVSGNNFEYTLEASKSLRQKPGDSTMTYLNKGQFYP 281

  Fly   428 IKLKKIGDLSLYRDKI--LKSVIKICFHERRLQFMEREQMQQW-----QQSRPGERIIEV-DVPL 484
            |.||::.........|  ::|||.:.|.|.:   ...:|::.|     :|....:|.|:: |...
Human   282 ITLKEVSSSEGIHHPISKVRSVIMVVFAEDK---SREDQLRHWKYWHSRQHTAKQRCIDIADYKE 343

  Fly   485 SYGLCHVSQPLSSGSLNTVEIFWDPLKEVGVYIKVNCISTEFTPKKHGGEKGVPFRLQIETYIEN 549
            |:   :....:...:.|.:...||...|..|:|.|||:||:|:.:|  |.||:|..:|::||..|
Human   344 SF---NTISNIEEIAYNAISFTWDINDEAKVFISVNCLSTDFSSQK--GVKGLPLNIQVDTYSYN 403

  Fly   550 TNSATASGSGGSNNSAIASGSGSSGSAAPASPERTPSAGSNGKQAVHAAACQIKVFKLKGADRKH 614
            ..|                                       .:.||.|.||||||..|||:||.
Human   404 NRS---------------------------------------NKPVHRAYCQIKVFCDKGAERKI 429

  Fly   615 KQDREKIQKRPQSEQEKFQPSYECTIMNDISLDLVMS 651
            :.:..|..||.....:   ||.:....:|:.:.|:.|
Human   430 RDEERKQSKRKGKCPD---PSSQVNAFSDVKVPLLPS 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gem	NP_610556.1	CP2	393..624	CDD:282385	69/246 (28%)
		SAM_CP2-like	739..805	CDD:188936
GRHL1	XP_006711945.1	CP2	235..442	CDD:282385	72/263 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144553
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840