DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment gem and Grhl3

DIOPT Version :9

Sequence 1:NP_610556.1 Gene:gem / 36064 FlyBaseID:FBgn0050011 Length:932 Species:Drosophila melanogaster
Sequence 2:NP_001013778.1 Gene:Grhl3 / 230824 MGIID:2655333 Length:603 Species:Mus musculus


Alignment Length:463 Identity:114/463 - (24%)
Similarity:187/463 - (40%) Gaps:111/463 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   210 IGQSENSPTASQSGDLPSKVAHQEKEKHKREKHSGRSSWSDDIGFDLNAEFNSNSYLN---NENF 271
            :|..|....:|.:|.        ..::.|:..||  ..:..|:     |...|.::|.   .|| 
Mouse    68 MGPKEKRILSSSTGG--------RNDQGKKFYHS--MDYEPDL-----APLESPTHLMKFLTEN- 116

  Fly   272 LSFSPTLTTLKQEPQTDQIKPSPKVSLDNASASPSIAIAKLDEVQNSPSQ-AISGQDSANGSGSA 335
            :|.||        ..|||:|.:..:.|:....:|    .|.:.|...||: ..|..||.....|.
Mouse   117 VSGSP--------DYTDQLKKNNLLGLEGVLPTP----GKTNTVPPGPSKLEASSMDSYLLPASD 169

  Fly   336 ANGKHDVNSGLACGCGSPQGSPLANAEYELNEKGKPQQLSVLDPAKIEIGSANGATHAEDH---- 396
            ......:||......|.|   |....:.:...|..||: |:|.|..::  ::......||:    
Mouse   170 IYDNGSLNSLFESIHGVP---PTQRWQPDSTFKDDPQE-SLLFPDILK--TSPDPPCPEDYPGLK 228

  Fly   397 -KFQYILAAATSIATKNNEETLTYLNQGQSYEIKLKKIG---DLSLYRDKILKSVIKICFHERRL 457
             .|:|.|.:..:|..|..|..:.|||:||.|.:.|:...   .|:|...|: |||:.:.|...::
Mouse   229 SDFEYTLGSPKAIHIKAGESPMAYLNKGQFYPVTLRTPAGGKGLALSSSKV-KSVVMVVFDNDKV 292

  Fly   458 QFMEREQMQQWQQSRP--GERIIEV-DVPLSYGLCHVSQPLSSGSLNTVEIFWDPLKEVGVYIKV 519
            ...:....:.|...:|  .:|:|:| |...::   :..|.:...:.|.:...|:..:|..|:|.|
Mouse   293 PVEQLRFWRHWHSRQPTAKQRVIDVADCKENF---NTVQHIEEVAYNALSFVWNVNEEAKVFIGV 354

  Fly   520 NCISTEFTPKKHGGEKGVPFRLQIETYIENTNSATASGSGGSNNSAIASGSGSSGSAAPASPERT 584
            ||:||:|:.:|  |.||||..|||:||                                      
Mouse   355 NCLSTDFSSQK--GVKGVPLNLQIDTY-------------------------------------- 379

  Fly   585 PSAGSNGKQAVHAAACQIKVFKLKGADRKHKQDREKIQKRPQSEQEKFQPSYECTIMNDISLDLV 649
             ..|:..::.||.|.||||:|..|||:||.:.|          |:::|:...:|.       |..
Mouse   380 -DCGAGTERLVHRAVCQIKIFCDKGAERKMRDD----------ERKQFRRKVKCP-------DSS 426

  Fly   650 MSATTTGC 657
            .:|...||
Mouse   427 NNAGIKGC 434

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gemNP_610556.1 CP2 393..624 CDD:282385 66/241 (27%)
SAM_CP2-like 739..805 CDD:188936
Grhl3NP_001013778.1 Transcription activation. /evidence=ECO:0000250|UniProtKB:Q8TE85 30..95 7/36 (19%)
CP2 213..421 CDD:282385 68/264 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167834673
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

Return to query results.
Submit another query.