Protein Alignment Pfk and pfkA

DIOPT Version :10

• Sequence 1: NP_523676.1
• Gene: Pfk / 36060
• FlyBaseID: FBgn0003071
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: NP_418351.1
• Gene: pfkA / 948412
• ECOCYCID: EG10699
• Length: 320
• Species: Escherichia coli
• Alignment Length: 358
• Identity: 132/358 - (36%)
• Similarity: 190/358 - (53%)
• Gaps: 44/358 - (12%)

  Fly   180 KGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWASVSSIIHRG 244
            |.:.|.|||||:.|||||:|..||.|:..|.:|..|.:||.|:.:  |.:.:.:..|||.:|:||
E. coli     3 KKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYE--DRMVQLDRYSVSDMINRG 65

  Fly   245 GTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLLDELVKNKTI 309
            ||.:||||..:||:...|..|..||.:|||..|||||||||..||        ..|.|:
E. coli    66 GTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGA--------MRLTEM------ 116

  Fly   310 TTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGR 374
                     ....:||.|:||||..|||.|||..|||..::||||.:..|:.||||..::|||||
E. coli   117 ---------GFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGR 172

  Fly   375 HCGYLALVGGLACEADFIFIPEMPPKVDWP-DRLCSQLAQERSAGQRLNIVIVAEGAMDREGHPI 438
            :||.|.|...:|...:|:.:||    |::. :.|.:::....:.|::..||.:.|       |..
E. coli   173 YCGDLTLAAAIAGGCEFVVVPE----VEFSREDLVNEIKAGIAKGKKHAIVAITE-------HMC 226

  Fly   439 TAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLD 503
            ..:::...|::....:.|.|||||:||||:|..:|||||.||||.|...|:......   .:.:.
E. coli   227 DVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGR---CVGIQ 288

  Fly   504 GNQAVRVPLMECVERTQAVAKAMAEKRWADAVK 536
            ..|.|...:::.:|..:...|.    .|.|..|
E. coli   289 NEQLVHHDIIDAIENMKRPFKG----DWLDCAK 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfk	NP_523676.1	6PF1K_euk	180..929	CDD:274152	132/358 (37%)
pfkA	NP_418351.1	PRK03202	2..319	CDD:235111	132/358 (37%)