DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pfk and PFK3

DIOPT Version :9

Sequence 1:	NP_001246234.1	Gene:	Pfk / 36060	FlyBaseID:	FBgn0003071	Length:	950	Species:	Drosophila melanogaster
Sequence 2:	NP_567742.1	Gene:	PFK3 / 828733	AraportID:	AT4G26270	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	423	Identity:	94/423 - (22%)
Similarity:	174/423 - (41%)	Gaps:	91/423 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 KKSAPKRKCGKSVDELRKCLRTMQDVIDFVHPVKPFKDKGLAVFTSGGDSQGMNAAVRACVRMAI 206
            :::.|::|.....||:..|                       :.|.||...|:|..:|..|....
plant    77 RRAGPRQKVYFESDEVHAC-----------------------IVTCGGLCPGLNTVIREIVSSLS 118

  Fly   207 YL-GCK-VYFIREGYQGMVDGGDCIQEANWAS-----VSSIIHRGGTIIGSARCQDFRERQGRLK 264
            |: |.| :..|..||:|       ....|..|     |:.|..|||||:|::     |......|
plant   119 YMYGVKRILGIDGGYRG-------FYAKNTVSLDSKVVNDIHKRGGTILGTS-----RGGHDTTK 171

  Fly   265 AANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLLDELVKNKTITTEQQEKFNVLHIVGLVGSI 329
            ..:::..|||..:.:|||||:..||        |::.|.::.:.:.         :.::|:..:|
plant   172 IVDSIQDRGINQVYIIGGDGTQRGA--------SVIFEEIRRRGLK---------VAVIGIPKTI 219

  Fly   330 DNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTF-IMEVMGRHCGYLSVVAGIIS-EADYV 392
            |||....|.:.|.|||:.....||:|....|.|.:... ::::|||:.|::::.|.:.| :.|..
plant   220 DNDIPVIDKSFGFDTAVEEAQRAINAAHVEAESIENGIGVVKLMGRYSGFIAMYATLASRDVDCC 284

  Fly   393 FLPESPPQADWPDRLVLKLEQE-RSAGQRLNIVIVAEGA----MDREGHPITAED---------- 442
            .:||||...:....|...:|:. :.:|..  ::::||||    |.:....:|.:|
plant   285 LIPESPFYLEGEGGLFEYIEKRLKESGHM--VLVIAEGAGQDLMSKSMESMTLKDASGNKLLKDV 347

  Fly   443 ---VKKVIDERLKHDARITVLGHVQ-----RGGNPSAFDRILACRMGAEATLALMEATKDSVPVV 499
               :.:.|.:.......:..|.::.     |....:|.|.:. |.:.|::  |:..|.......:
plant   348 GLWLSQSIKDHFNQKKMVMNLKYIDPTYMIRAVPSNASDNVY-CTLLAQS--AVHGAMAGYTGYI 409

  Fly   500 ISLDGNQAVRVPLMECVERTQAVAKAMAEKRWA 532
            ..|...:...:|.....|:...|  .:.::.||
plant   410 SGLVNGRQTYIPFYRITEKQNHV--VITDRMWA 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pfk	NP_001246234.1	PFK	178..914	CDD:294137	89/387 (23%)
Pfk	NP_001246234.1	6PF1K_euk	180..929	CDD:274152	89/385 (23%)
PFK3	NP_567742.1	PLN02564	5..487	CDD:178178	94/423 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	81	1.000	Domainoid score	I2941
eggNOG	1	0.900	-	-		E1_COG0205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000489
OrthoInspector	1	1.000	-	-		otm2441
orthoMCL	1	0.900	-	-		OOG6_100319
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.710