Protein Alignment Pfk and Pfkp

DIOPT Version :10

• Sequence 1: NP_523676.1
• Gene: Pfk / 36060
• FlyBaseID: FBgn0003071
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: XP_063132788.1
• Gene: Pfkp / 60416
• RGDID: 61893
• Length: 839
• Species: Rattus norvegicus
• Alignment Length: 810
• Identity: 458/810 - (56%)
• Similarity: 582/810 - (71%)
• Gaps: 71/810 - (8%)

  Fly   180 KGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWASVSSIIHRG 244
            |.:.|.|||||:|||||||||.|||.||.|.|||||.||||||||||..|.||.|..||||:..|
  Rat    25 KAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGMVDGGSNIVEAKWECVSSILQVG 89

  Fly   245 GTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLLDELVKNKTI 309
            ||||||||||.||.|:||||||.||::.|||||.|||||||||||||||:|||.||:||.||..|
  Rat    90 GTIIGSARCQAFRSREGRLKAACNLVRLGITNLCVIGGDGSLTGANLFRKEWSGLLEELAKNGEI 154

  Fly   310 TTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGR 374
            .::..:|...|::||:||||||||||||||||||:|||||||.:|||.:||.||||||::|||||
  Rat   155 DSDTVKKHAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGR 219

  Fly   375 HCGYLALVGGLACEADFIFIPEMPPKVDWPDRLCSQLAQERSAGQRLNIVIVAEGAMDREGHPIT 439
            ||||||||..|||.||::|:||.||:..|.:.:|.:|::.|:..:||||:||:|||:|.:..|||
  Rat   220 HCGYLALVSALACGADWVFLPESPPEEGWEEEMCLKLSENRARKKRLNIIIVSEGAIDTQNKPIT 284

  Fly   440 AEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLDG 504
            :|.:|:::...|..|.|:|:||||||||.|||||||||.|||.||.|||:|||.::...|:||.|
  Rat   285 SEKIKELVVTNLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLEATPETPACVVSLRG 349

  Fly   505 NQAVRVPLMECVERTQAVAKAMAEKRWADAVKLRGRSFERNLETYKMLTRLKP----PKENFDAD 565
            |||||:||||||:.||.|.|||.|:|:.:||||||||||.||.|||.|...:|    ||.|.:
  Rat   350 NQAVRLPLMECVQMTQDVQKAMDERRFDEAVKLRGRSFEGNLNTYKRLAIKEPDDKIPKSNCN-- 412

  Fly   566 GKGIEGYRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGW 630
                    :|::::||||.||||||||.||..|..|..::.|.||.:||..|.::|:||.||.||
  Rat   413 --------VAIINVGAPAAGMNAAVRSAVRVGIAEGHKMFAIYDGFDGLANGQIKEIGWGDVGGW 469

  Fly   631 VGQGGAYLGTKRTLPEGKFKE-IAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIV 694
            .||||:.|||||||| ||:.| ||.::....|..||||||||:|....::|..|:.:..||:|:|
  Rat   470 TGQGGSILGTKRTLP-GKYLEKIAEQMHSKNINALLIIGGFEAYLGLLELAAARNKHEAFCVPMV 533

  Fly   695 VIPSTISNNVPGTEFSLGCDTGLNEIT-------------------------------------- 721
            ::|:|:||||||::||:|.||.||.||
  Rat   534 MVPATVSNNVPGSDFSIGADTALNTITDGFHSAVLLSEARNSHDEFCIPICVLAATISNDVPGTD 598

  Fly   722 -------------EICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSI 773
                         :.||||:|||.|||||||:||||||||||||.:.|||.|||||||:||:|.|
  Rat   599 ISIGSDTSLNVVVQTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEQFDI 663

  Fly   774 KDLQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQGGS 838
            :|||.:|.|:..||...:.|||:||||..|.||:|||||:||||||||:|.||.|:||||||||:
  Rat   664 RDLQSNVMHLTEKMKTSIQRGLVLRNENCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGA 728

  Fly   839 PTPFDRNMGTKMAAKCVDWLAAQIKANIDANGV-VNCKSPDTATLLGIVSRQYRFSPLVDLIAET 902
            |:|||||.|||::||.::|::|::|.   ::|. ....|.|:..:|||..|...|.|:.:|...|
  Rat   729 PSPFDRNFGTKISAKAMEWISAKLKG---SHGTGKKFVSDDSICVLGIQKRDLLFKPVAELRKAT 790

  Fly   903 NFDQRIPKKQWWLRLRPLLRILAKHDSAYE 932
            :|:.||||:||||:|||:::||||::::|:
  Rat   791 DFEHRIPKQQWWLKLRPIMKILAKYEASYD 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfk	NP_523676.1	6PF1K_euk	180..929	CDD:274152	457/805 (57%)
Pfkp	XP_063132788.1	None