Protein Alignment Pfk and pfkpb

DIOPT Version :10

• Sequence 1: NP_523676.1
• Gene: Pfk / 36060
• FlyBaseID: FBgn0003071
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: XP_068074152.2
• Gene: pfkpb / 561416
• ZFINID: ZDB-GENE-070912-634
• Length: 833
• Species: Danio rerio
• Alignment Length: 808
• Identity: 467/808 - (57%)
• Similarity: 583/808 - (72%)
• Gaps: 66/808 - (8%)

  Fly   180 KGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWASVSSIIHRG 244
            |.:.|.|||||:|||||||||.|||.||:|.|||||.|||||||||||.|:||:|.||||::..|
Zfish    16 KCIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIHEGYQGMVDGGDNIKEASWESVSSMLQVG 80

  Fly   245 GTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLLDELVKNKTI 309
            ||:||||||:|||..:|||.||.||:|||||||.|||||||||||||||:|||.||||||::..|
Zfish    81 GTVIGSARCKDFRTHEGRLHAALNLVQRGITNLCVIGGDGSLTGANLFREEWSGLLDELVQSGQI 145

  Fly   310 TTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGR 374
            :.:..:..:.|||||:||||||||||||||||||:|||||||.:|||.:||.||||||::|||||
Zfish   146 SEDAAQTHSALHIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGR 210

  Fly   375 HCGYLALVGGLACEADFIFIPEMPPKVDWPDRLCSQLAQERSAGQRLNIVIVAEGAMDREGHPIT 439
            ||||||||..|||.||::.|||.|||..|.:::|.:|::.|:..:||||:||||||:|:...|||
Zfish   211 HCGYLALVSALACGADWVLIPERPPKDGWEEQMCQKLSENRADKKRLNIIIVAEGAIDQNNKPIT 275

  Fly   440 AEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLDG 504
            .:.:|.::..||..|.|:|:||||||||.|||||||||.|||.||.|||:||:..:...|:||.|
Zfish   276 TDHIKDLVVSRLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLEASPGTPACVVSLCG 340

  Fly   505 NQAVRVPLMECVERTQAVAKAMAEKRWADAVKLRGRSFERNLETYKMLTRLK----PPKENFDAD 565
            ||||||||||||:.||.|.|||.|||:.:||||||||||.||.|||:|:..|    .|..:|:
Zfish   341 NQAVRVPLMECVQMTQEVQKAMDEKRFEEAVKLRGRSFENNLNTYKLLSHRKIDTELPHSSFN-- 403

  Fly   566 GKGIEGYRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGW 630
                    :||:::||||.||||||||.||..|..|..::.::||.||...|.::|:.|.||.||
Zfish   404 --------VAVLNVGAPAAGMNAAVRSAVRVGITEGHTMFAVSDGFEGFYKGQIKEIKWGDVGGW 460

  Fly   631 VGQGGAYLGTKRTLPEGKFKEIAARLKEFKIQGLLIIGGFESY------------HA-------- 675
            .||||:.||||||||.....:||.:::...|..||:|||||:|            ||
Zfish   461 TGQGGSLLGTKRTLPAKHVDKIAEQMRIHNINALLVIGGFEAYLGLMELQAARSKHAELCVPMVM 525

  Fly   676 ---------------AG----------------QIADQRDNYPQFCIPIVVIPSTISNNVPGTEF 709
                           .|                |:.|.|..|.:||:|:.::|:||||||.||:.
Zfish   526 VPATVSNNIPGSDLSIGADTAINAITDAFESLLQLVDARSRYEEFCVPLCMLPATISNNVSGTDL 590

  Fly   710 SLGCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIK 774
            |:|.||.||.|.|.||||:|||.|||||||:|||||||||||||:.|||.||||||||||.|.|:
Zfish   591 SIGADTSLNAIVETCDRIKQSASGTKRRVFIIETMGGYCGYLATVGGLAAGADAAYIYEEPFDIR 655

  Fly   775 DLQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQGGSP 839
            |||.:|.|:..||...:.|||:||||.::|||:|||||:||||||||:|.||.|:||||||||:|
Zfish   656 DLQSNVEHLTEKMKTSIQRGLVLRNENSNENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAP 720

  Fly   840 TPFDRNMGTKMAAKCVDWLAAQIKANIDANGVVNCKSPDTATLLGIVSRQYRFSPLVDLIAETNF 904
            :|||||.|||:|||.:.|::.::| ....:|.|...:.|:|.|||:..|...|.|:|.|..||:|
Zfish   721 SPFDRNFGTKIAAKAMQWISKKLK-EFYRDGRVFANTEDSACLLGMRRRALLFQPVVQLKDETDF 784

  Fly   905 DQRIPKKQWWLRLRPLLRILAKHDSAYE 932
            ..||||:|||||||||::||||:.::|:
Zfish   785 VHRIPKEQWWLRLRPLMKILAKYKTSYD 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfk	NP_523676.1	6PF1K_euk	180..929	CDD:274152	466/803 (58%)
pfkpb	XP_068074152.2	None