Protein Alignment Pfk and pfkma

DIOPT Version :10

• Sequence 1: NP_523676.1
• Gene: Pfk / 36060
• FlyBaseID: FBgn0003071
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: NP_001004575.1
• Gene: pfkma / 447836
• ZFINID: ZDB-GENE-040912-135
• Length: 784
• Species: Danio rerio
• Alignment Length: 759
• Identity: 440/759 - (57%)
• Similarity: 570/759 - (75%)
• Gaps: 13/759 - (1%)

  Fly   171 VHPVKPFKDKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWA 235
            |.|.|....:.:||.|||||:|||||||||.||:.:|.|.||:|:.|||||:|||||.|:.|.|.
Zfish     9 VDPTKMGVGRAIAVLTSGGDAQGMNAAVRATVRVGLYTGAKVFFVHEGYQGLVDGGDHIRPATWE 73

  Fly   236 SVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLL 300
            |||.::..|||:||||||:||:.|:||||||.||::.|||||.||||||||||||:||.|||.||
Zfish    74 SVSMMLQLGGTVIGSARCKDFQTREGRLKAAYNLVKLGITNLCVIGGDGSLTGANIFRTEWSDLL 138

  Fly   301 DELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQR 365
            .:.|....||.|:.:..:.|:|||:||||||||||||||||||:|||||||.:|:|::||.||||
Zfish   139 KDHVSKGKITKEEAKASSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDSITTTAQSHQR 203

  Fly   366 TFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVDWPDRLCSQLAQERSAGQRLNIVIVAEGA 430
            .||:|||||||||||||..|||.||::|||||||...|.:.||.:|.:.|:||.|||::||||||
Zfish   204 AFILEVMGRHCGYLALVTALACGADWVFIPEMPPDDGWEEHLCRRLTETRNAGSRLNVIIVAEGA 268

  Fly   431 MDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDS 495
            :::||.|||.:.:|.::.:||..|.|.|:||||||||.||||||:|..|||.||.:||:|||.::
Zfish   269 INKEGQPITCDQLKDLVTKRLGFDTRATILGHVQRGGTPSAFDRVLGSRMGVEAVMALLEATPET 333

  Fly   496 VPVVISLDGNQAVRVPLMECVERTQAVAKAMAEKRWADAVKLRGRSFERNLETYKMLTRLKPP-- 558
            ...|:||.||||||:||||||:.|:.|..||.|.|:.|||||||||||.|..|||:|..::||
Zfish   334 PACVVSLTGNQAVRLPLMECVQVTKDVTIAMNEGRFDDAVKLRGRSFENNWNTYKLLAHIRPPDK 398

  Fly   559 KENFDADGKGIEGYRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELG 623
            |.|.:          :|::::|||..|||||||:.||..|.:|..:..::||.|||....:..:.
Zfish   399 KSNIN----------VAILNVGAPCAGMNAAVRAAVRIGIIQGHNMLAVHDGFEGLAQAKIEPIT 453

  Fly   624 WSDVSGWVGQGGAYLGTKRTLPEGKFKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQ 688
            |:.|..|.|:||:.|||||.||....:||:..:.::.|..|:||||||::....::...|:.|.:
Zfish   454 WNTVGDWTGKGGSDLGTKRLLPGKYMEEISLNIAKYNIHALVIIGGFEAFSGGLEMVQGREKYEE 518

  Fly   689 FCIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLAT 753
            .|||:|:||:|:||||||::||:|.||.||.||..||||:|||.|||||||:|||||||||||||
Zfish   519 LCIPMVIIPATVSNNVPGSDFSIGADTALNTITTTCDRIKQSAAGTKRRVFIIETMGGYCGYLAT 583

  Fly   754 LAGLAGGADAAYIYEEKFSIKDLQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEE 818
            ::||:.|||||||:||||.|:||:::|.|:..||...|.||||||||.::.||:||||:.|||||
Zfish   584 MSGLSAGADAAYIFEEKFGIRDLERNVEHLVEKMKTTVKRGLILRNENSNSNYTTDFIFNLYSEE 648

  Fly   819 GKGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAAQIKANIDANGVVNCKSPDTATLL 883
            |||:|.||.|:||||||||:|||||||..|||.||.|.||..::| :...:|.:...:||:|.:|
Zfish   649 GKGVFDCRKNVLGHMQQGGTPTPFDRNFATKMGAKAVLWLTEKLK-DCYRHGRIFANTPDSACVL 712

  Fly   884 GIVSRQYRFSPLVDLIAETNFDQRIPKKQWWLRLRPLLRILAKH 927
            |:..|.....||.:|..||:|:.||||.||||:|||:::||||:
Zfish   713 GMRKRGLVLQPLAELKEETDFEHRIPKSQWWLKLRPIMKILAKY 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pfk	NP_523676.1	6PF1K_euk	180..929	CDD:274152	437/750 (58%)
pfkma	NP_001004575.1	Eukaryotic_PFK	15..771	CDD:238389	437/753 (58%)