DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3zeta and ywhae

DIOPT Version :9

Sequence 1:	NP_001014515.1	Gene:	14-3-3zeta / 36059	FlyBaseID:	FBgn0004907	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_001008156.1	Gene:	ywhae / 493518	XenbaseID:	XB-GENE-996375	Length:	255	Species:	Xenopus tropicalis

Alignment Length:	239	Identity:	162/239 - (67%)
Similarity:	196/239 - (82%)	Gaps:	2/239 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIE 69
            ::|:||.:||||||:||||:|.::||.|....|||:.|||||||||||||:||||:|||:|||||
Frog     3 EREDLVYRAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIE 67

  Fly    70 QKTE--ASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYL 132
            ||.|  ....|.::.||||:.||.||:.||.::|.:|||:|||.|::.||||||.||||||:|||
Frog    68 QKEENKGGEDKLKMIREYRQMVEAELKSICNDILDVLDKHLIPAANSGESKVFYYKMKGDYHRYL 132

  Fly   133 AEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQ 197
            ||.|.|:.|....::|..||:.|.||:..::.|||||||||||||||||||||||||:||:|||.
Frog   133 AEFAQGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKA 197

  Fly   198 AFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAE 241
            ||||||||||||:|:||||||||||||||||||||||.|||..|
Frog   198 AFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEE 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	156/230 (68%)
ywhae	NP_001008156.1	14-3-3_epsilon	4..233	CDD:206757	155/228 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1059
SonicParanoid	1	1.000	-	-		X206
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960