DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3zeta and ywhah

DIOPT Version :9

Sequence 1:	NP_001014515.1	Gene:	14-3-3zeta / 36059	FlyBaseID:	FBgn0004907	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_998329.1	Gene:	ywhah / 406443	ZFINID:	ZDB-GENE-040426-2191	Length:	246	Species:	Danio rerio

Alignment Length:	247	Identity:	178/247 - (72%)
Similarity:	202/247 - (81%)	Gaps:	10/247 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIE 69
            |:|:|:|:|:||||:|||||||.|||.|||....||||:||||||||||||||||||||||||||
Zfish     3 DREQLIQRARLAEQAERYDDMASAMKLVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIE 67

  Fly    70 QKTEA--SARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKA--SNPESKVFYLKMKGDYYR 130
            |||.|  :.:|.:|.|.|||.|||||..:|.:||.|||:|||...  :..|||||||||||||||
Zfish    68 QKTAADGNEKKLELVRVYRETVEKELESVCQDVLTLLDQYLIKNCDETQVESKVFYLKMKGDYYR 132

  Fly   131 YLAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLA 195
            ||||||||:.|.:.|:.|:.||::||||||| |..|||||||||||||||||||.|:|::|||||
Zfish   133 YLAEVATGEKRASAVESSEGAYKEAFDISKG-MPATHPIRLGLALNFSVFYYEIQNAPEQACQLA 196

  Fly   196 KQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGD 247
            |:||||||..||.||||||||||||||||||||||||||.|     ..||||
Zfish   197 KEAFDDAIGHLDNLNEDSYKDSTLIMQLLRDNLTLWTSDQQ-----DSEGGD 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	171/232 (74%)
ywhah	NP_998329.1	14-3-3	3..246	CDD:295170	178/247 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595889
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18860
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.820