DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3zeta and ywhaqb

DIOPT Version :9

Sequence 1:	NP_001014515.1	Gene:	14-3-3zeta / 36059	FlyBaseID:	FBgn0004907	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_958892.1	Gene:	ywhaqb / 335195	ZFINID:	ZDB-GENE-030131-7135	Length:	245	Species:	Danio rerio

Alignment Length:	245	Identity:	192/245 - (78%)
Similarity:	216/245 - (88%)	Gaps:	0/245 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSI 68
            :|:.||:||||||||:|||||||..||||||.|.|||||||||||||||||||||||:|||||||
Zfish     1 MDRTELIQKAKLAEQAERYDDMASCMKSVTEAGSELSNEERNLLSVAYKNVVGARRSAWRVISSI 65

  Fly    69 EQKTEASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYLA 133
            |||||.:.:|.|:.:||||:||.|||:||.:||.||:||||..:|||||||||||||||||||||
Zfish    66 EQKTEGNDKKLQMVKEYREKVESELRDICNDVLELLNKYLIENSSNPESKVFYLKMKGDYYRYLA 130

  Fly   134 EVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQA 198
            |||.||.:...:::||.|||.||||||.:||||||||||||||||||:|||||||:|||.|||||
Zfish   131 EVAAGDDKKATIENSQDAYQKAFDISKTEMQPTHPIRLGLALNFSVFFYEILNSPEKACSLAKQA 195

  Fly   199 FDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN 248
            ||:||||||||||:||||||||||||||||||||||...||.|..|||:|
Zfish   196 FDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSDNAPDEGEGGEGGEN 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	183/228 (80%)
ywhaqb	NP_958892.1	14-3-3_theta	1..234	CDD:206759	185/232 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	370	1.000	Domainoid score	I860
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	395	1.000	Inparanoid score	I1921
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR18860
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X206
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.940