DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3zeta and ywhae1

DIOPT Version :9

Sequence 1:	NP_001014515.1	Gene:	14-3-3zeta / 36059	FlyBaseID:	FBgn0004907	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_997770.1	Gene:	ywhae1 / 322060	ZFINID:	ZDB-GENE-030131-779	Length:	255	Species:	Danio rerio

Alignment Length:	239	Identity:	165/239 - (69%)
Similarity:	196/239 - (82%)	Gaps:	2/239 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIE 69
            |:|:||.:||||||:||||:|..:||.|....|||:.|||||||||||||:||||:|||:|||||
Zfish     3 DREDLVYQAKLAEQAERYDEMVDSMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIE 67

  Fly    70 QKTE--ASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYL 132
            ||.|  ....|.::.||||:.||.||:.||.::|.:|||:|||.|::.||||||.||||||:|||
Zfish    68 QKEENKGGEDKLKMIREYRQTVENELKSICNDILDVLDKHLIPAANSGESKVFYYKMKGDYHRYL 132

  Fly   133 AEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQ 197
            ||.|||:.|....::|..||:.|.||:...:||||||||||||||||||||||||||:||:|||.
Zfish   133 AEFATGNDRKEAAENSLVAYKAASDIAMTDLQPTHPIRLGLALNFSVFYYEILNSPDRACRLAKA 197

  Fly   198 AFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAE 241
            ||||||||||||:|:||||||||||||||||||||||.|||..|
Zfish   198 AFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEE 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	159/230 (69%)
ywhae1	NP_997770.1	14-3-3_epsilon	4..233	CDD:206757	157/228 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100283
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1059
SonicParanoid	1	1.000	-	-		X206
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.760