DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3zeta and ywhabl

DIOPT Version :9

Sequence 1:	NP_001014515.1	Gene:	14-3-3zeta / 36059	FlyBaseID:	FBgn0004907	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_955856.1	Gene:	ywhabl / 321729	ZFINID:	ZDB-GENE-030131-448	Length:	245	Species:	Danio rerio

Alignment Length:	245	Identity:	188/245 - (76%)
Similarity:	222/245 - (90%)	Gaps:	0/245 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSI 68
            :||.|||||||||||:|||||||.|||:|||..:|||||||||||||||||||||||||||:|||
Zfish     1 MDKSELVQKAKLAEQAERYDDMAAAMKAVTEGDIELSNEERNLLSVAYKNVVGARRSSWRVVSSI 65

  Fly    69 EQKTEASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYLA 133
            |||.|.|.:|||:.:||||::||||:|||.:||.||||||||||:..||:||||||||||:||||
Zfish    66 EQKMEGSDKKQQMVKEYREKIEKELKEICNDVLVLLDKYLIPKATPAESRVFYLKMKGDYFRYLA 130

  Fly   134 EVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQA 198
            |||.|:.:|:::.:||.||:|||:|||.:||||||||||||||||||||||||||::||:|||.|
Zfish   131 EVAVGEEKNSIIGNSQEAYKDAFEISKAEMQPTHPIRLGLALNFSVFYYEILNSPEQACKLAKTA 195

  Fly   199 FDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN 248
            ||:||||||:|||:||||||||||||||||||||||.||:..:.:||.:|
Zfish   196 FDEAIAELDSLNEESYKDSTLIMQLLRDNLTLWTSDNQGEGEDAEEGREN 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	181/228 (79%)
ywhabl	NP_955856.1	14-3-3	2..230	CDD:295170	180/227 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	370	1.000	Domainoid score	I860
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56528
Inparanoid	1	1.050	395	1.000	Inparanoid score	I1921
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	1	1.000	-	-		otm25005
orthoMCL	1	0.900	-	-		OOG6_100283
Panther	1	1.100	-	-	O	PTHR18860
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X206
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.980