DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3zeta and LOC298795

DIOPT Version :9

Sequence 1:	NP_001014515.1	Gene:	14-3-3zeta / 36059	FlyBaseID:	FBgn0004907	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_001013963.1	Gene:	LOC298795 / 298795	RGDID:	1359510	Length:	248	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	162/247 - (65%)
Similarity:	195/247 - (78%)	Gaps:	7/247 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSI 68
            :::..|:||||||||:|||:|||..|||..|.|.|||.|||||||||||||||.:||:|||:|||
  Rat     1 MERASLIQKAKLAEQAERYEDMAAFMKSAVEKGEELSFEERNLLSVAYKNVVGGQRSAWRVLSSI 65

  Fly    69 EQK--TEASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRY 131
            |||  .|.|..|....:||||:||.|||.:|..||||||.:||..|...||:|||||||||||||
  Rat    66 EQKINEEGSEEKGPEVKEYREKVETELRGVCDTVLGLLDSHLIKGAGEAESRVFYLKMKGDYYRY 130

  Fly   132 LAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAK 196
            ||||||||.:..::|.:::|||:|.||||.:|.||:|||||||||||||:|||.|.|::|..|||
  Rat   131 LAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANRPEEAISLAK 195

  Fly   197 QAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEA-----EPQ 243
            ..||:|:|:|.||:||||||||||||||||||||||::..|:|.     |||
  Rat   196 TTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTAENAGEEGGEAPEEPQ 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	157/230 (68%)
LOC298795	NP_001013963.1	14-3-3	1..234	CDD:295170	157/232 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353728
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18860
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.860