Protein Alignment 14-3-3zeta and SFN

DIOPT Version :9

• Sequence 1: NP_001014515.1
• Gene: 14-3-3zeta / 36059
• FlyBaseID: FBgn0004907
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_006133.1
• Gene: SFN / 2810
• HGNCID: 10773
• Length: 248
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 162/245 - (66%)
• Similarity: 198/245 - (80%)
• Gaps: 4/245 - (1%)

  Fly     4 VDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSI 68
            :::..|:||||||||:|||:|||..||...|.|.|||.|||||||||||||||.:|::|||:|||
Human     1 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSI 65

  Fly    69 EQKT--EASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRY 131
            |||:  |.|..|....|||||:||.||:.:|..||||||.:||.:|.:.||:|||||||||||||
Human    66 EQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRY 130

  Fly   132 LAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAK 196
            ||||||||.:..::|.:::|||:|.||||.:|.||:|||||||||||||:|||.|||::|..|||
Human   131 LAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAK 195

  Fly   197 QAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEA--EPQE 244
            ..||:|:|:|.||:||||||||||||||||||||||:|..|:|.  .|||
Human   196 TTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPQE 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	156/230 (68%)
SFN	NP_006133.1	14-3-3_sigma	1..242	CDD:206756	159/240 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18860
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.820