Protein Alignment 14-3-3zeta and SFN

DIOPT Version :10

• Sequence 1: NP_476885.2
• Gene: 14-3-3zeta / 36059
• FlyBaseID: FBgn0004907
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_006133.1
• Gene: SFN / 2810
• HGNCID: 10773
• Length: 248
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 162/245 - (66%)
• Similarity: 198/245 - (80%)
• Gaps: 4/245 - (1%)

  Fly     4 VDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSI 68
            :::..|:||||||||:|||:|||..||...|.|.|||.|||||||||||||||.:|::|||:|||
Human     1 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSI 65

  Fly    69 EQKT--EASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRY 131
            |||:  |.|..|....|||||:||.||:.:|..||||||.:||.:|.:.||:|||||||||||||
Human    66 EQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRY 130

  Fly   132 LAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAK 196
            ||||||||.:..::|.:::|||:|.||||.:|.||:|||||||||||||:|||.|||::|..|||
Human   131 LAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAK 195

  Fly   197 QAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEA--EPQE 244
            ..||:|:|:|.||:||||||||||||||||||||||:|..|:|.  .|||
Human   196 TTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPQE 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3zeta	NP_476885.2	14-3-3	5..234	CDD:470464	156/230 (68%)
SFN	NP_006133.1	14-3-3_sigma	1..242	CDD:206756	159/240 (66%)