DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 14-3-3zeta and Ywhaz

DIOPT Version :9

Sequence 1:	NP_001014515.1	Gene:	14-3-3zeta / 36059	FlyBaseID:	FBgn0004907	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_001240734.1	Gene:	Ywhaz / 22631	MGIID:	109484	Length:	245	Species:	Mus musculus

Alignment Length:	245	Identity:	200/245 - (81%)
Similarity:	222/245 - (90%)	Gaps:	0/245 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSI 68
            :||.|||||||||||:|||||||..||||||.|.|||||||||||||||||||||||||||:|||
Mouse     1 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSI 65

  Fly    69 EQKTEASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYLA 133
            |||||.:.:|||:||||||::|.|||:||.:||.||:|:|||.||.|||||||||||||||||||
Mouse    66 EQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKMKGDYYRYLA 130

  Fly   134 EVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQA 198
            |||.||.:..:||.||.|||:||:|||.:||||||||||||||||||||||||||:|||.|||.|
Mouse   131 EVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTA 195

  Fly   199 FDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN 248
            ||:||||||||:|:|||||||||||||||||||||||||||||..|||:|
Mouse   196 FDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	187/228 (82%)
Ywhaz	NP_001240734.1	14-3-3_beta_zeta	2..230	CDD:206758	186/227 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	366	1.000	Domainoid score	I924
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56528
Inparanoid	1	1.050	404	1.000	Inparanoid score	I1891
Isobase	1	0.950	-	0.861654	Normalized mean entropy	S35
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	1	1.000	-	-		otm42769
orthoMCL	1	0.900	-	-		OOG6_100283
Panther	1	1.100	-	-	O	PTHR18860
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1059
SonicParanoid	1	1.000	-	-		X206
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.820