DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jra and jund

DIOPT Version :9

Sequence 1:	NP_001260844.1	Gene:	Jra / 36057	FlyBaseID:	FBgn0001291	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001121814.1	Gene:	jund / 564873	ZFINID:	ZDB-GENE-070725-2	Length:	283	Species:	Danio rerio

Alignment Length:	266	Identity:	105/266 - (39%)
Similarity:	149/266 - (56%)	Gaps:	44/266 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 KRPGSLDL---NSKSAKNKRIFAPLVINSPDLSSKTVNTPDLEKILLSNNLMQTPQPGK--VFPT 116
            |:..||:|   ||.|.|.....|..::|||||....:.:|:||::::.:|.|.|..|..  ::|.
Zfish    22 KKDMSLNLDDQNSSSLKPDLRDAEGILNSPDLGLLKLASPELERLIIQSNGMVTTTPTSQFIYPK 86

  Fly   117 KAGPVTVEQLDFGRGFEEALHNLHTNSQ--AFPSANSAANSAANNTTAAAMTA---VNNGISGGT 176
            .   |:.|| :|..||.:||.:||..:|  ..|......|..||::|:.|:.|   |...:|
Zfish    87 S---VSDEQ-EFAEGFVKALEDLHKQNQLNGGPCVPPTLNRLANSSTSLALNADLPVYTNLS--- 144

  Fly   177 FTYTNMTEGFSV--------------------IKDEP------VNQASSPTVNPIDMEAQEKIKL 215
             ||.:.|..:|.                    :||||      .:...||.::||||:.||:||.
Zfish   145 -TYGSTTVNYSTDTIPFPPPPPAHPMSAQPQPLKDEPQTVPDMQSFGDSPPLSPIDMDTQERIKA 208

  Fly   216 ERKRQRNRVAASKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGC 280
            |||:.|||:||||||||||||||:|||:||.||.:|.:|||....|::.||||||:||.|:..||
Zfish   209 ERKKLRNRIAASKCRKRKLERISRLEDKVKSLKSQNTELASTASVLREQVAQLKQRVMNHVNNGC 273

  Fly   281 TVPPNS 286
            .:.||:
Zfish   274 QLLPNT 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jra	NP_001260844.1	Jun	<76..>144	CDD:281890	24/69 (35%)
		bZIP_Jun	214..274	CDD:269844	40/59 (68%)
		coiled coil	215..266	CDD:269844	32/50 (64%)
jund	NP_001121814.1	Jun	20..194	CDD:281890	51/179 (28%)
		bZIP_Jun	207..267	CDD:269844	40/59 (68%)
		coiled coil	208..259	CDD:269844	32/50 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583930
Domainoid	1	1.000	92	1.000	Domainoid score	I7564
eggNOG	1	0.900	-	-		E1_KOG0837
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4287
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1090460at2759
OrthoFinder	1	1.000	-	-		FOG0001331
OrthoInspector	1	1.000	-	-		otm25062
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11462
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4616
SonicParanoid	1	1.000	-	-		X1044
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.890