DRSC/TRiP Functional Genomics Resources

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Protein Alignment Jra and JUNB

DIOPT Version :9

Sequence 1:NP_001260844.1 Gene:Jra / 36057 FlyBaseID:FBgn0001291 Length:372 Species:Drosophila melanogaster
Sequence 2:NP_002220.1 Gene:JUNB / 3726 HGNCID:6205 Length:347 Species:Homo sapiens


Alignment Length:314 Identity:104/314 - (33%)
Similarity:151/314 - (48%) Gaps:72/314 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 GPMSL-DFQ--SPNLNTSTPNPN---KRPGSLDLNSKSAKNKRIFAPLVINSPDLSSKTVNTPDL 95
            |.:|| |::  .|:|..:..:|.   |.||:.....:.......|:..  .|...:|..:.:.:|
Human    25 GGLSLHDYKLLKPSLAVNLADPYRSLKAPGARGPGPEGGGGGSYFSGQ--GSDTGASLKLASSEL 87

  Fly    96 EKILLSNN---LMQTP-QPGKVFPTK-----------AGPVTVEQLDFGRGFEEALHNLHTNSQA 145
            |::::.|:   :..|| .||:.|..:           .|.||.||..|..||.:||.:||..:..
Human    88 ERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGGAGGAGGGVTEEQEGFADGFVKALDDLHKMNHV 152

  Fly   146 FPS---------------------------ANSAANSAANNTTAAAMTAVNNGIS---------- 173
            .|.                           .|.::.|.|:.::..|..||..|.|          
Human   153 TPPNVSLGATGGPPAGPGGVYAGPEPPPVYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLP 217

  Fly   174 ------GGTFTYTNMTEGFSVIKDEP--VNQASS----PTVNPIDMEAQEKIKLERKRQRNRVAA 226
                  ||......:..|.|..|:||  |.:|.|    |.|:||:||.||:||:||||.|||:||
Human   218 HAPPFAGGHPAQLGLGRGASTFKEEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAA 282

  Fly   227 SKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGC 280
            :||||||||||::|||:||.||.||..|:|....|::.||||||:||.|::.||
Human   283 TKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGC 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
JraNP_001260844.1 Jun <76..>144 CDD:281890 22/82 (27%)
bZIP_Jun 214..274 CDD:269844 39/59 (66%)
coiled coil 215..266 CDD:269844 31/50 (62%)
JUNBNP_002220.1 Jun 5..257 CDD:309180 52/233 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 51..73 4/23 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 239..260 8/20 (40%)
Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 268..295 21/26 (81%)
bZIP_Jun 270..329 CDD:269844 38/58 (66%)
coiled coil 271..322 CDD:269844 31/50 (62%)
Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 296..324 14/27 (52%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165149785
Domainoid 1 1.000 89 1.000 Domainoid score I7846
eggNOG 1 0.900 - - E1_KOG0837
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 138 1.000 Inparanoid score I4527
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1090460at2759
OrthoFinder 1 1.000 - - FOG0001331
OrthoInspector 1 1.000 - - otm41026
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11462
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4616
SonicParanoid 1 1.000 - - X1044
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
1211.930

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