Protein Alignment Jra and JUN

DIOPT Version :10

• Sequence 1: NP_001260844.1
• Gene: Jra / 36057
• FlyBaseID: FBgn0001291
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_002219.1
• Gene: JUN / 3725
• HGNCID: 6204
• Length: 331
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 106/313 - (33%)
• Similarity: 149/313 - (47%)
• Gaps: 81/313 - (25%)

  Fly    32 PVGEEGPMSLDFQSPNLNTSTPNPNKRPGSLDLNSKSAKNKRIFAPLVINSPDLSSKTVNTPDLE 96
            |.|...|..|. ||..||.:.|     .|||..:.: |||..:     :.|||:....:.:|:||
Human    25 PYGYSNPKILK-QSMTLNLADP-----VGSLKPHLR-AKNSDL-----LTSPDVGLLKLASPELE 77

  Fly    97 KILL---SNNLMQTPQPGKVFPTKAGPVTVEQLDFGRGFEEALHNLHTNSQAFPSANSAA---NS 155
            ::::   :.::..||.|.:....|  .||.||..|..||..||..||:.: ..||..|||   |.
Human    78 RLIIQSSNGHITTTPTPTQFLCPK--NVTDEQEGFAEGFVRALAELHSQN-TLPSVTSAAQPVNG 139

  Fly   156 AANNTTAAAMTAVNNGISGGTFT---------YTNMTE--------------------------- 184
            |  ...|.|:.:|..|...|.|:         |.|::.
Human   140 A--GMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQ 202

  Fly   185 ------------------GFSVIKDEPVN----QASSPTVNPIDMEAQEKIKLERKRQRNRVAAS 227
                              ....:|:||..    ...:|.::|||||:||:||.||||.|||:|||
Human   203 QQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAAS 267

  Fly   228 KCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGC 280
            ||||||||||::||::||.||.:|.:|||....|::.||||||:||.|:.:||
Human   268 KCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGC 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jra	NP_001260844.1	Jun	34..>144	CDD:461108	35/112 (31%)
		bZIP_Jun	214..274	CDD:269844	39/59 (66%)
		coiled coil	215..266	CDD:269844	31/50 (62%)
JUN	NP_002219.1	Jun	6..240	CDD:461108	54/231 (23%)
		Interaction with PAGE4. /evidence=ECO:0000269|PubMed:26242913	150..223		6/72 (8%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	252..279		22/26 (85%)
		bZIP_Jun	254..314	CDD:269844	39/59 (66%)
		coiled coil	255..306	CDD:269844	31/50 (62%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	280..308		13/27 (48%)