DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jra and Junb

DIOPT Version :9

Sequence 1:	NP_001260844.1	Gene:	Jra / 36057	FlyBaseID:	FBgn0001291	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_068608.2	Gene:	Junb / 24517	RGDID:	2944	Length:	344	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	103/318 - (32%)
Similarity:	146/318 - (45%)	Gaps:	100/318 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 KRPGSLDLNSKSAKNKRIFAP-LVINSPD--------------------------------LSSK 88
            :.||||.|:     :.::..| |.:|..|                                .|.|
  Rat    22 RSPGSLSLH-----DYKLLKPTLALNLADPYRGLKGPGARGPGPEGSGAGSYFSGQGSDTGASLK 81

  Fly    89 TVNTPDLEKILLSNN---LMQTP-QPGKVFPTK--------AGPVTVEQLDFGRGFEEALHNLHT 141
            ..:| :||::::.|:   :..|| .||:.|..:        .|.||.||..|..||.:||.:||.
  Rat    82 LAST-ELERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGGTGGGVTEEQEGFADGFVKALDDLHK 145

  Fly   142 NSQAFPS---------------------------ANSAANSAANNTTAAAMTAVNNGIS------ 173
            .:...|.                           .|.::.|.|:..:..:.|||..|.|
  Rat   146 MNHVTPPNVSLGASGGPQAGPGGVYAGPEPPPVYTNLSSYSPASAPSGGSGTAVGTGSSYPTATI 210

  Fly   174 ----------GGTFTYTNMTEGFSVIKDEP--VNQASS----PTVNPIDMEAQEKIKLERKRQRN 222
                      ||......::.|.|..|:||  |.:|.|    |.|:||:||.||:||:||||.||
  Rat   211 SYLPHAPPFAGGHPAQLGLSRGASAFKEEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRN 275

  Fly   223 RVAASKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGC 280
            |:||:||||||||||::|||:||.||.||..|:|....|::.||||||:||.|::.||
  Rat   276 RLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGC 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jra	NP_001260844.1	Jun	<76..>144	CDD:281890	27/112 (24%)
		bZIP_Jun	214..274	CDD:269844	39/59 (66%)
		coiled coil	215..266	CDD:269844	31/50 (62%)
Junb	NP_068608.2	Jun	5..254	CDD:397861	51/237 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..75		0/23 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..202		6/20 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	237..257		8/19 (42%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	265..292		21/26 (81%)
		bZIP_Jun	267..326	CDD:269844	38/58 (66%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	293..321		14/27 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343682
Domainoid	1	1.000	89	1.000	Domainoid score	I7653
eggNOG	1	0.900	-	-		E1_KOG0837
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4456
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1090460at2759
OrthoFinder	1	1.000	-	-		FOG0001331
OrthoInspector	1	1.000	-	-		otm45162
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11462
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1044
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.900