DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jra and F19B2.6

DIOPT Version :9

Sequence 1:	NP_001260844.1	Gene:	Jra / 36057	FlyBaseID:	FBgn0001291	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_507885.2	Gene:	F19B2.6 / 184664	WormBaseID:	WBGene00008945	Length:	807	Species:	Caenorhabditis elegans

Alignment Length:	406	Identity:	75/406 - (18%)
Similarity:	126/406 - (31%)	Gaps:	143/406 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AGSSGATAIQIIPKTEPVGEEGPMSLDFQSPNLNTSTPNPNKRPGSLD-----LNSKS----AKN 71
            ||..|........:..|.|...|.:.....||   ..||||...|..|     ||..:    .:|
Worm   399 AGMKGCCVKDQYHEPAPSGYHPPQAQSNCYPN---HPPNPNMNAGDQDRQHVQLNFYTDPGFQQN 460

  Fly    72 KRIFAPLVINSPDLSSKTVNTPDLEKILLSNNLMQTPQPGKVFPTKAGPVTVEQLDFGRGFEEAL 136
            ..:        |....:...|..::.....||     ||..:|.:..|..||.....| .::|.:
Worm   461 SHV--------PYEMQQGFQTTGMQGSYQQNN-----QPELLFDSNNGNQTVNNAPNG-NYQEPV 511

  Fly   137 H---------NLHTNSQAFPSANSAANSAANNTTAAAMTAVNNGISGGTFTYTNMTEGFSVIKDE 192
            :         |.:.|...|||                                          |:
Worm   512 YPLLQEGPTWNNNDNHDYFPS------------------------------------------DD 534

  Fly   193 PVNQASSPTVNPIDMEAQEKIKLERKRQRNRVAASKCRKRK---LERISKLEDRVK-----VLKG 249
            .::|.|.   .|:.:|:   |:.:.||.:|::.|.|..::|   |:...|..:.||     :|..
Worm   535 SMSQTSQ---EPVSVES---IRKKTKRAKNKLEARKSLQKKKDDLKASRKSWEEVKINHNNILSS 593

  Fly   250 ENVDLASIVKNLKDHVAQL------KQQVMEHIAAGCTVPPNSTDQXHLELSAGENDEEDV---- 304
            .|    |..:|:|....|:      .|||:     |......|.|: ....:..|||::::
Worm   594 NN----SNEENIKTAFDQVLYPCFTNQQVI-----GTFNIIRSYDEVQEGFAQFENDKQNIISKV 649

  Fly   305 -------------------------ALETETPSNPEDPEQPMPLEFFSSASTGALELEGSASQDI 344
                                     ..||:..:..||.::        :...|..:|.|......
Worm   650 DYLMKTDRNLKKLRMAKEVSEKQWEQFETDKKNRKEDDKK--------NKINGGNKLNGKTKIVS 706

  Fly   345 SLTNSELLEEESDNEQ 360
            |:|.:.......|.::
Worm   707 SITIATRCSRSKDKKE 722

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jra	NP_001260844.1	Jun	<76..>144	CDD:281890	14/76 (18%)
		bZIP_Jun	214..274	CDD:269844	19/73 (26%)
		coiled coil	215..266	CDD:269844	15/58 (26%)
F19B2.6	NP_507885.2	Med15	<37..>351	CDD:255446
F19B2.6	NP_507885.2	235kDa-fam	<546..>754	CDD:130673	37/197 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157685
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930