DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut4 and HXT1

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_011962.1	Gene:	HXT1 / 856494	SGDID:	S000001136	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	478	Identity:	114/478 - (23%)
Similarity:	221/478 - (46%)	Gaps:	70/478 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ALGAFCLGAVIGW-SGPVENEVKNSNAYNFTPR-------------QTEWGLVGSLMTLGAAFSC 64
            |.|.|    :.|| :|.:...|..:   :|..|             :...||:.|:..:|.|..
Yeast    73 AFGGF----IFGWDTGTISGFVAQT---DFLRRFGMKHHDGSHYLSKVRTGLIVSIFNIGCAIG- 129

  Fly    65 IPVGVLIGKI----GRKTTMLILLPPFFIGWLLILLAS--HIAMLLLGRFVVGFCGGAFCVTCPM 123
               |:::.|:    ||:..:::::..:.|| ::|.:||  ......:||.:.|...|...|..||
Yeast   130 ---GIVLAKLGDMYGRRIGLIVVVVIYTIG-IIIQIASINKWYQYFIGRIISGLGVGGITVLSPM 190

  Fly   124 YVTEIAQVQYRGTMGCFFQLLIVFGILYAFVVGGFVKTFYFNIACAI-LPVIF----FVL--MIF 181
            .::|:|..:.|||:...:|::|..||...:......|.:..::...: |.:.|    |::  |:|
Yeast   191 LISEVAPSEMRGTLVSCYQVMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMMF 255

  Fly   182 MPESPIFLAQKGKAEKAEKSL----------KFLRGKDADVSGELKEMSAEGQKEKASVGKILCR 236
            :||||.:|.:.|:.::|..||          .:::.:...:...::||.|.|   .||.|::...
Yeast   256 VPESPRYLVEAGRIDEARASLAKVNKCPPDHPYIQYELETIEASVEEMRAAG---TASWGELFTG 317

  Fly   237 RITL-KGLFLSIGLMLFQQMTGINAIIFYSTFIFETAG--STLEPRISTIIVGIVQAIATIISIL 298
            :..: :...:.|.:...||:||.|...:|.|.:|:..|  .:.|   ::|:.|:|...:|..|:.
Yeast   318 KPAMFQRTMMGIMIQSLQQLTGDNYFFYYGTIVFQAVGLSDSFE---TSIVFGVVNFFSTCCSLY 379

  Fly   299 VIEKVGRKILLLVSACMMGISTLIMALYFGML----------MKSGVGWLALIAVCVFIIGFSLG 353
            .:::.||:..|:..|..| :...::....|:.          ...|.|...::..|.:|..|:..
Yeast   380 TVDRFGRRNCLMWGAVGM-VCCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATT 443

  Fly   354 FGPVPWLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFV 418
            :.|:.:::::|.|...||:...|||...||.:.|:::...|.:...|.....: :|.|..|.|:.
Yeast   444 WAPIAYVVISECFPLRVKSKCMSIASAANWIWGFLISFFTPFITGAINFYYGY-VFMGCMVFAYF 507

  Fly   419 FILFLIPETKGKTLNEIQAKMGE 441
            ::.|.:|||||.:|.|:.....|
Yeast   508 YVFFFVPETKGLSLEEVNDMYAE 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	113/471 (24%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	97/412 (24%)
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	113/474 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342315
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I1037
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	7	6.690